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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Synthesis of Lutein
Published Tuesday, July 21, 2015BackgroundLutein is a dietary carotenoid present in most fruits and vegetables and has been shown to play an important role in eye health and the prevention of age-related macular degeneration (AMD). These health benefits make it an important dietary supplement. However, currently lutein is commercially produced by extracting it from...
Categories: Natural Compounds
Keyword(s): Nutraceutical
Docket: LS-2008-036
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A Novel Method for Production of Rare Carotenoids from Commercially Available Lutein
Published Tuesday, July 21, 2015Anhydrolutein, a-cryptoxanthin, b-cryptoxanthin and zeaxanthin are among the 12 major dietary carotenoids which are found in human serum, milk, major organs, and tissues. Industrial production of a wide range of purified carotenoids is of great importance in view of the role of carotenoids in the prevention of chronic diseases like cancer, age-...
Categories: Natural Compounds
Keyword(s): Nutraceutical
Docket: LS-2000-040
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Naturally Derived Herbicide Adjuvants for Glyphosate-Resistant Weeds
Published Monday, November 24, 2014BackgroundGlyphosate (i.e. Roundup®) is a broad-spectrum herbicide that is widely used due to its effectiveness and low toxicity. However, after decades of use, some plants have developed a resistance to glyphosate. These glyphosate-resistant weeds can create economic problems for farmers. For example, the presence of one giant ragweed...
Categories: Natural Compounds, Agricultural
Keyword(s): 525
Docket: LS-2014-162
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Use of EM 1412 as a vaginal microbicide for HIV, HPV and HSV transmission
Published Friday, November 7, 2014Cervical dysplasia is the existence of abnormal cells in the cervix, which may indicate a pre-cancerous condition. In the United States, 250,000 to 1 million women are diagnosed with cervical dysplasia annually in which 30% to 50% possibly progressing to invasive cancer without treatment. In order to address this issue...
Investigator(s): Niharika Khanna, Neil Frazier, Ru Chi Huang
Categories: Therapeutics, Repurpose Drug, Natural Compounds
Docket: NK-2004-057
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Natural Method for the Production of Neoagarobiose
Published Sunday, June 29, 2014BackgroundIncreasingly consumers are interested in purchasing products that contain natural ingredients. One market that has seen an increase in natural ingredients is personal health care products. The perceived health benefits from natural materials and avoidance of unnecessary chemicals is often what drives these purchasing decisions...
Categories: Natural Compounds
Keyword(s): cosmetics, natural production, natural products
Docket: LS-2006-055
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Inhibition of Breast Cancer Metastases using Natural Extracts from Colocasia Esculenta (Taro).
Published Wednesday, May 28, 2014Studies link breast cancer, the second leading cause of cancer-related mortality in US women, with the occurrence of metastatic disease and spread. However, the majority of current therapies focus on the treatment of solid tumors with very little focus on targeting the metastatic process. Due to the significant correlation of secondary tumors...
Investigator(s): Namita Kundu, Amy Fulton
Categories: Therapeutics, Biologics, Natural Compounds
Keyword(s): breast cancer, cancer
Docket: NK-2009-001
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Everything We Say It is: Essential Water
Published Tuesday, July 12, 2011BackgroundWater based products with vitamins, minerals and other nutrients have a wide-ranging niche in the marketplace. These products are not only ideal for consumers interested in having a sugar-free or reduced sugar drink but also for disadvantaged groups in desperate need of a wholesome and easily consumable nutritive drink. The...
Categories: Natural Compounds
Keyword(s): Water based nutridrink, nutri-drink, nutridrink, vitamin water, fat-soluble vitamin water
Docket: LS-2011-028
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Egg-Based Dietary Supplement for the Prevention and Treatment of Infectious Diseases
Published Tuesday, July 12, 2011BackgroundInfluenza vaccination significantly reduces the morbidity and mortality of seasonal influenza. However, its efficacy is limited in high-risk populations such as infants, the elderly and the immunosuppressed. The lack of preexisting immunity to pandemic or zoonotic (spread from animals to humans) strains can lead to severe...
Categories: Natural Compounds
Keyword(s): Influenza vaccine, vaccine, Egg-based dietary supplement, Prevention and Treatment of Infectious diseases, Infectious diseases
Docket: LS-2011-046
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Natural Additives to Stabilize Food During Freeze-Thaw Cycles
Published Thursday, April 16, 2009Hydrocolloid Gum Mixture as Freeze-Thaw Stabilizer and Moisture Retainer Xanthan and Curdlan gums are food additives produced by microbial fermentation. They are widely used in the food industry to increase the quality of foods by stabilizing, thickening and emulsifying products such as ice cream, salad dressings and surimi. The...
Categories: Natural Compounds
Keyword(s): xanthan, curdlan, gum
Docket: LS-2008-018
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Synthesis Method for Curcumin
Published Wednesday, April 15, 2009Turmeric or "yellow root" is a general term for plants and plant materials having a high content of curcuminoids, compounds that have a strong coloring effect and which are used extensively in the coloring of e.g. food products. The term "curcuminoids" includes curcumin (C), reddish orange; demothoxy curcumin (DMC), orange-yellow and bis-...
Categories: Chemical, Natural Compounds
Keyword(s): Dietary supplement, natural extracts, health, food additives
Docket: LS-2006-046