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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Noninvasive Characterization of Mechanical Properties of Materials and Tissue using Magnetic Resonance Techniques
Published Wednesday, February 6, 2019Many diseases alter the mechanical properties of tissue. Accordingly, the mechanical properties can serve as biomarkers for disease, diagnosis, and tumor assessment. While some larger diseased tissues or abnormalities near the surface of a patient can be detected by palpitation, many are located deep within the patient or too small to...
Investigator(s): Bruce Yu, Mark Taraban, Yue Feng
Categories: Devices, Software + Algorithm, Sensors/Monitors, Industrial Processing, Other
Keyword(s): MRI, NMR, diagnostic
Docket: BY-2012-013
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Nano-structured Metal-Enhanced Fluorescence (MEF-spot)-Based Sensing, Imaging and Assay
Published Friday, February 24, 2017This invention describes an improved method for conducting a bioassay using fluorescence intensity or lifetime fluorescent emissions. This new method avoids the need of complex enzymatic and biochemical amplification of the fluorescence signal. Although it has applicability over a wide range of bioassays, the method...
Investigator(s): Henryk Szmacinski, Joseph R. Lakowicz
Categories: Research Tools, Antibodies, & Reagents, Sensors/Monitors
Keyword(s): Cytokine assay, immunoassay
Docket: HS-2012-047, HS-2015-098
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A Microbial Biosensor for Ethylene Gas
Published Monday, May 27, 2013BackgroundEthylene is a gas that serves as a hormone in plants and is critical for many aspects of plant growth and development such as stimulating or regulating the ripening of fruit, the opening of flowers, and the shedding of leaves. Environmental cues such as flooding, drought, chilling, wounding, and pathogen attack can induce...
Categories: Sensors/Monitors
Keyword(s): ethylene, gas, ethylene gas, gas detection, ethylene detection, detection, hormone, biosensor, sensor, ethylene receptor, receptor
Docket: LS-2012-090
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Data Communication Through Pipes and Structures By Dispersive Elastic Waves
Published Sunday, March 4, 2012BackgroundEmbedded sensors in large civil structures for structural health monitoring applications require data communication capabilities between sensor nodes. Conventional communication modalities include electromagnetic waves or acoustical waves. However, ultrasonic guided elastic waves that can propagate on solid structures such as pipes...
Categories: Sensors/Monitors
Keyword(s): structural health monitoring embedded sensor strain gauge corrosion
Docket: IS-2011-081
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Porous Monolith Sensing Elements for Molecular and Biomolecular Detection
Published Wednesday, August 17, 2011BackgroundIn flow-through immunoassays, capillaries and microfluidic channels have side walls upon which are anchored particular antibody probes chosen to capture specific antigens present in a fluid being measured. Antigen capture efficiency is limited by the surface areas of the sidewalls available for immobilizing the antibody probes...
Categories: Sensors/Monitors, Microfluidics
Keyword(s): immunoassay, porous, pores, surface area, microfluidic, SERS, polymer, monomer
Docket: PS-2010-029