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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Microdevice for the Detection of Sequence Differences in Biological Samples
Published Tuesday, November 4, 2014BackgroundWith the advancements in biomedical research, accurate sequencing of biological samples is becoming of greater importance. The completion of the Human Genome Project has highlighted the potential of single nucleotide polymorphisms (SNPs) in DNA while the increase in protein-based therapies has increased interest in the...
Categories: Diagnostics, Devices, Research Tools, Antibodies, & Reagents
Keyword(s): Gene sequencing, protein sequencing, lab-on-chip
Docket: LS-2014-076
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Zona Incerta Stimulation for Chronic Pain Relief
Published Thursday, May 29, 2014Central pain syndrome (CPS) is a debilitating condition affecting with lesions or dysfunction in the central nervous system. CPS is a neurological disorder resulting from damage to or dysfunction of the pain-conducting pathways of the central nervous system. The patented invention describes a novel method for treating CPS regions of the...
Investigator(s): Asef Keller, Raimi Quiton, Peter Murray, Radi Masri, Jessica Lucas
Categories: Devices, Methods of Treatment
Keyword(s): chronic, pain, device, neurostimulation
Docket: AK-2009-044
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Surgical Abdominal Wall Model
Published Thursday, May 29, 2014The Surgical Abdominal Wall (SAW) model is a physical/mechanical model developed by researchers at UMB to simulate laparoscopic ventral hernia repair (LVHR) and other abdominal wall surgical procedures. Materials were carefully chosen to simulate skin, tissue, organs, and adhesions associated with abdominal wall morphology and pathology....
Investigator(s): Adrian Park, Ivan George, F. Jacob Seagull
Categories: Devices
Docket: AP-2008-024
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Subwavelength Resolution Optical Microscopy
Published Thursday, May 29, 2014Optical microscopy, both transmission and fluorescence, has limited spatial resolution due to well-known limits of diffraction. In addition, few methods are available to increase spatial resolution. The invention describes a novel and a simple method of increasing optical resolution. The present technology can be specifically used to image...
Investigator(s): Joseph Lakowicz, Mustafa Chowdury, Chandran Subanagayam
Categories: Devices, Imaging devices
Docket: JL-2007-088
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Straight Expandable Polypectomy Forceps
Published Thursday, May 29, 2014Endoscopic biopsy forceps are routinely used for the resectioning of small, sessile, sub-centimeter polyps of the gastrointestinal tract. Originally invented to biopsy and sample mucosa, these forceps remain inadequate for the resectioning of entire polyps and often require multiple passes for complete removal. In order to resolve this issue,...
Investigator(s): Florence M. Aslinia, M.D., MS Eric Goldberg
Categories: Devices, Surgical devices
Keyword(s): device
Docket: FA-2012-062
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Real-time tracking of tumor motion during radiation treatment using a dynamic couch
Published Thursday, May 29, 2014A patient couch is designed to track movement of a target tumor in the patient (due to biological functions such as respiration), and to make compensatory moves so that the radiation treatment site is stabilized.
Investigator(s): Warren DýSouza, Xinsheng Yu, Mohan Suntharali, William Regine
Categories: Devices, Imaging devices
Keyword(s): radiation, tumor
Docket: WD-2005-055
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Medical Image Registration and Applications
Published Wednesday, May 28, 2014Hardware-accelerated image registration has been developed by Dr. Raj Shekhar's group at UMB, a novel computing solution for automatic and accurate registration (spatial alignment) of three-dimensional medical images of any modality and any anatomy. Using these innovations, the computing period for image registration is considerably shorter (...
Investigator(s): Raj Shekhar
Categories: Devices, Imaging devices
Keyword(s): medical image
Docket: RS-2006-006
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Manometry Monitoring Device for Use in Virtual Colonoscopy (VC) Examinations
Published Wednesday, May 28, 2014Virtual colonoscopy (VC) is an effective medical procedure for use in identifying polyps and cancers in the bowel. Typically, this procedure involves cleansing the patient's bowel, distending the patient's colon by insufflation, scanning the patient, and analyzing the acquired images. However, the proper amount of distention following...
Investigator(s): David Vining
Categories: Devices, Imaging devices
Keyword(s): Virtual Colonoscopy, colonscopies
Docket: DV-2007-108
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MINIR: Minimally Invasive Neurosurgical Intracranial Robot
Published Wednesday, May 28, 2014Brain tumors are the second leading cause of cancer-related deaths in children and the most feared complication of metastatic spread. The unfavorable location of many tumors, usually deep or otherwise inaccessible to conventional neurosurgical techniques, places patients at an undue risk for neurological complications from complex brain surgery...
Investigator(s): Rao Gullapalli, Jaydev P. Desai, J. Marc Simard, Mingyen Ho
Categories: Devices, Surgical devices
Keyword(s): brain tumors, tumor
Docket: RG-2012-008
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Inhibition Of Metastatic Tumors
Published Wednesday, May 28, 2014Cancer is the second-leading cause of death in the United States. Death of cancer patients is most often caused by metastatic spread of tumor cells from the primary tumor site through the bloodstream where the cells lie dormant for long periods. These dormant cells will invade secondary sites such as the lung, liver or kidney where they develop...
Investigator(s): Stuart Martin, Rebecca Whipple, Agnes Cheung
Categories: Devices, Imaging devices, Software + Algorithm, Healthcare, Education/Training/Multimedia
Docket: SM-2006-059