Search Technologies
Displaying 191 - 200 of 226 results
Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
Search by keyword:
-
Method for the identification of microbial community signature as diagnostic markers, including specific applications for the diagnosis of Crohn's disease and ulcerative colitis.
Published Wednesday, May 28, 2014The two most common forms of inflammatory bowel disease (IBD), are Crohn's and ulcerative colitis, disease states in which the body elicits an immune response within the gastrointestinal tract causing chronic pain, inflammation, and intestinal distress. Though distinctly different, the two diseases often share common symptoms making a...
Investigator(s): W. Florian Fricke, James White
Categories: Diagnostics
Keyword(s): Crohn's disease, ulcerative colitis
Docket: WF-2012-079
-
Method for Teaching and Evaluating decision-Making Skills Through Computer-Based Simulation
Published Wednesday, May 28, 2014Researchers in the Department of Surgery, University of Maryland School of Medicine, have developed a software tool to aid faculty in teaching students clinical decision-making in patient care as well as the interrelationships between medicine and other disciplines. The software is used to design medical case studies of patients that recreate...
Investigator(s): Bruce Jarrell, Craig Skinner, John Raczek, Noble Jarrell, John Flowers
Categories: Software + Algorithm, Healthcare, Education/Training/Multimedia
Keyword(s): Computer-Based Simulation, simulation, teaching, evaluating
Docket: BJ-2004-032
-
Method and Assay for Early Diagnosis of Prostate Cancer
Published Wednesday, May 28, 2014For well over 20 years, digital rectal examination (DRE) combined with the measurement of prostate specific antigens (PSA) have remained the most recommended screening tests for the detection of prostate cancer for men over 40. However, both exams remain highly unreliable due to the high prevalence of false positive and negative results. To...
Investigator(s): Hafiz Ahmed, Gerardo Vasta
Categories: Diagnostics
Keyword(s): prostate cancer, cancer
Docket: HA-2010-082
-
Melanoma Oncolytic Virotherapy by the HSV-2 Mutant delta-PK
Published Wednesday, May 28, 2014Oncolytic viruses are replication-conditional viruses with relative tumor selectivity and are a therapeutic strategy designed to reduce tumor burden by direct cell lysis; however, their modest clinical efficacy may be related to poor virus replication within the tumors. The present invention is based on the hypothesis that virotherapy...
Investigator(s): Laure Aurelian, Aric Colunga, Jennifer Laing
Categories: Therapeutics, Biologics
Keyword(s): Melanoma, Virotherapy
Docket: LA-2009-096
-
Medication Management Instrument for Deficiencies in the Elderly (MedMalDE)
Published Wednesday, May 28, 2014Denise Orwig and Nicole Brandt at University of Maryland Baltimore, have developed a questionnaire for the use of nonmedical personnel (untrained caregivers such as family members, volunteers, or staff aides) to assess an older adult's ability to manage medications in the home setting.
Investigator(s): Denise Orwig, Nicole Brandt
Categories: Software + Algorithm, Healthcare
Keyword(s): software, education
Docket: DO-2002-045
-
Medical Image Registration and Applications
Published Wednesday, May 28, 2014Hardware-accelerated image registration has been developed by Dr. Raj Shekhar's group at UMB, a novel computing solution for automatic and accurate registration (spatial alignment) of three-dimensional medical images of any modality and any anatomy. Using these innovations, the computing period for image registration is considerably shorter (...
Investigator(s): Raj Shekhar
Categories: Devices, Imaging devices
Keyword(s): medical image
Docket: RS-2006-006
-
Manometry Monitoring Device for Use in Virtual Colonoscopy (VC) Examinations
Published Wednesday, May 28, 2014Virtual colonoscopy (VC) is an effective medical procedure for use in identifying polyps and cancers in the bowel. Typically, this procedure involves cleansing the patient's bowel, distending the patient's colon by insufflation, scanning the patient, and analyzing the acquired images. However, the proper amount of distention following...
Investigator(s): David Vining
Categories: Devices, Imaging devices
Keyword(s): Virtual Colonoscopy, colonscopies
Docket: DV-2007-108
-
MINIR: Minimally Invasive Neurosurgical Intracranial Robot
Published Wednesday, May 28, 2014Brain tumors are the second leading cause of cancer-related deaths in children and the most feared complication of metastatic spread. The unfavorable location of many tumors, usually deep or otherwise inaccessible to conventional neurosurgical techniques, places patients at an undue risk for neurological complications from complex brain surgery...
Investigator(s): Rao Gullapalli, Jaydev P. Desai, J. Marc Simard, Mingyen Ho
Categories: Devices, Surgical devices
Keyword(s): brain tumors, tumor
Docket: RG-2012-008
-
Lower extremity gain scores (LEGS)
Published Wednesday, May 28, 2014The LEGS is a portable performance-based assessment designed to assess recovery after a hip fracture by providing concrete norms that can serve as benchmarks over the course of recovery.
Investigator(s): Jay Magaziner, Sheryl Zimmerman, William Hawkes, J. Richard Hebel
Categories: Software + Algorithm, Healthcare
Keyword(s): hip fracture, LEGS
Docket: JM-2003-019
-
Live Attenuated Salmonella Paratyphi A Vaccine
Published Wednesday, May 28, 2014With the emergence of antibiotic resistant strains and increase in frequency of enteric fever caused by Salmonella enterica serovar Paratyphi A, there is a critical need for a prophylactic vaccine, as none is currently available. Typhoid fever and paratyphoid fever are clinically indistinguishable, patients having a rash and fever which can...
Investigator(s): Chris Vindurampulle, Eileen Barry, Myron Levine
Categories: Vaccine
Keyword(s): vaccine, paratyphoid
Docket: CV-2006-034