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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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ANALYTE-SENSITIVE PROBES AND CONTACT LENS FOR DIAGNOSIS OF OCULAR PATHOLOGIES
Published Thursday, November 9, 2023Summary The patent introduces a contact lens integrated with analyte-sensitive probes for diagnosing ocular pathologies through the detection of specific analytes in basal tears. This non-invasive, real-time monitoring technology has applications in medical diagnostics and...
Investigator(s): Joseph R. Lakowicz, Ramachandram Badugu, E. Albert Reece
Categories: Devices, Imaging devices, Diagnostics, Imaging, Healthcare
Keyword(s): Analyte-sensitive probes, fluorescence, Diagnostics, Real-time monitoring
Docket: JL-2019-091
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One Dimensional Photonic Crystals for Enhanced Fluorescence Based Sensing, Imaging and Assays
Published Monday, November 6, 2023Summary This patent presents a leap in photonic devices, using one-dimensional photonic crystals (1DPCs) to amplify fluorescence in biological assays. The innovation promises a thousand-fold enhancement of evanescent fields, tunable emission, and cost-effective production. It has...
Investigator(s): Joseph R. Lakowicz, Ramachandram Badugu
Categories: Diagnostics, Imaging
Keyword(s): Photonic crystals, fluorescence enhancement, Bloch Surface Waves, sensing, imaging, assays, dielectric materials, biomolecule detection, real-time quantification.
Docket: JL-2013-117
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System and Method for Diagnosis, Monitoring, and Treatment of Obstructive Sleep Apnea
Published Monday, September 30, 2019Sleep Apnea treatment represents a $6 billion market in the United States. Current treatment methods suffer from poor compliance rates. The inventors have proposed a novel ultrasound device to diagnose and treat sleep apnea.
Investigator(s): Amal Isaiah, Jeffrey Wolf
Categories: Devices, Imaging devices, Diagnostics, Imaging, Methods of Treatment
Keyword(s): sleep apnea
Docket: AI-2018-039
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eLVOTD: Estimation of the Left Ventricular Outflow Tract Diameter
Published Monday, May 15, 2017The left ventricular outflow tract diameter (LVOTD) is one of two measurements needed to calculate cardiac stroke volume and cardiac output (CO). CO is an important measure of heart function and can help determine the need for inotropic support of the heart. In combination with mean arterial blood pressure, CO can also be used to determine the...
Investigator(s): Sarah Murthi
Categories: Diagnostics, Imaging, Software + Algorithm
Keyword(s): Acute care
Docket: SM-2017-060
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Method of Visualizing Drusen in the Eye
Published Thursday, October 27, 2016Drusen are yellow fatty protein deposits under the retina. The formation of drusen increases the risk of a person developing “dry” age-related macular degeneration (dry AMD). The inventor has previously disclosed in published work the surprising finding that these deposits contained tiny hydroxyapatite (HAP)...
Investigator(s): Richard Thompson, Imre Lengyel
Categories: Diagnostics, Imaging
Keyword(s): Ophthalmology, Geriatric, diagnostic
Docket: RT-2012-010, RT-2016-112