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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Nanoparticle-Based Artificial Antigen Presenting Cell for the Modulation of Natural Killer T (NKT) Cells
Published Thursday, February 23, 2017Natural killer T (NKT) cells constitute an important subset of T cells that can both, directly and indirectly, mediate antitumor immunity. It has been reported that the number of NKT cells in cancer patients can be 47% lower than those found in healthy patients. An effective mean of generating populations of NKT cells would be therapeutically...
Investigator(s): Tonya Webb, James East, Carolyn Morris
Categories: Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): Cancer Immunotherapy, adaptive immunotherapy
Docket: TW-2012-105
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DART Therapeutic Platform Technology for Treating Fn14-Positive Cancers
Published Monday, June 13, 2016Therapeutic nanoparticles (NPs) approved for clinical use in cancer patients provide only modest improvements in patient survival, likely due to a number of delivery challenges. The discovery of unique cell surface proteins associated with certain tumors has facilitated new approaches for nanocarrier design and payload delivery; specifically,...
Investigator(s): Anthony Kim, Jeffrey Winkles, Graeme Woodworth
Categories: Therapeutics, Nanotechnology + Nanoparticles + Nanomaterials
Keyword(s): blood brain barrier, diagnostic, Therapeutic, brain cancer, nanoparticle
Docket: GW-2014-120; AK-2019-061