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  • Sintact Medication Systems

    Sintact Medical Systems, Inc.

    Sintact Medical Systems, Inc. develops non-resorbable films that separate adjacent organs from adhering to each other after surgery. 

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    Category:Biomaterials

    Established:

  • Rakta Therapeutics, Inc.

    Rakta Therapeutics, Inc. has licensed the rights to a series of small molecules for the treatment of leishmaniasis, one of the World Health Organizations neglected tropical diseases. Spread by bites sandflies, the Leshmania protozoan are the cause of the disease. Leishmaniasis affects millions of people worldwide and results in tens of thousands of deaths each year. Previous research at the University of Maryland has identified that Leshmania were unable to synthesize heme, a molecule essential for cellular function. Since these protozoans cannot synthesize heme, the parasitic protozoan must absorb heme from their hosts. Through further collaboration with the University of Maryland, Baltimore, the researchers developed inhibitors of the Leshmania heme transport mechanism. Rakta Therapeutics has licensed these inhibitors with the goal of developing the compounds into effective treatments for leishmaniasis. 

    Category:Small molecules

    Established:

  • Calabash Biosciences

    Calabash Biosciences is based on a technology that uses novel molecular containers for efficient drug delivery applications. These molecular containers first conceived and created by University of Maryland’s (UMCP) investigators improve the solubilization of drugs and allow them to be easily accessed by the body. The enhanced solubilization makes them superior to the currently available cyclodextrixn class of compounds. Calabash was initiated as a follow-up to collaborative research efforts between investigators at the UMCP and Mass General Hospital. Their collaboration involved the study of drug solubilization applications, in particular, the reversal of neuromuscular blocking (NMB) or anesthesia inducing agents. Calabash is in the process of developing new formulations for a variety of currently available drugs in the market. 

    Category:Small molecules

    Established:

  • StemSynergy Logo

    StemSynergy Therapeutics, Inc.

    StemSynergy Therapeutics, Inc. (SSTI) is a biopharmaceutical company focused on the discovery of small-molecule drugs that target developmental pathways fundamental to cancer and tissue regeneration. 

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    Category:Small molecules

    Established:

  • Behavioral Activation Tech, LLC

    Behavioral Activation Tech, LLC

    Behavioral Activation Tech, LLC (BAT) has licensed technological adaptations of evidence-based psychological treatments for low mood and associated disorders. BAT has received funding from both the Maryland Innovation Initiative (MII) and the National Institute of Mental Health’s Small Business Technology Transfer (STTR) program to develop mobile application adaptations of Brief Behavioral Activation Treatment for Depression, an evidence-based psychotherapy. The overall goal of BAT’s products is to disseminate evidence-based treatments for mental health concerns.

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    Category:Methods of Treatment

    Established:

  • Mobile Comfort Inc. Logo

    Mobile Comfort Inc.

    Mobile Comfort, Inc. is a University of Maryland start-up created to commercialize a personal air conditioning device called RoCo, short for roving comforter. Mobile Comfort has licensed the RoCo technology and associated intellectual property which was developed in the Clark School’s Center for Environmental Energy Engineering (CEEE) with funding from the Department of Energy. RoCo is a battery powered personal air conditioning system which provides supreme personal thermal management for people in inadequately or un-conditioned environments by storing its waste heat internally so it does not require fixed ventilation. It is equipped with a robotic nozzle, is portable, and can used anywhere.

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    Category:Other

    Established:

  • RoboSeed Logo

    RoboSeed, LLC

    Low cost, reliable, micro-scale air vehicle for commercial and military applications. “an innovative micro-air vehicle (MAV) technology that took an intriguing approach in a soon to be burgeoning MAV and UAV market.

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    Category:Aerospace

    Established:

  • North American Wave Engine Corporation

    North American Wave Engine Corporation

    North American Wave Engine Corporation, a University of Maryland start-up, has licensed a university developed technology that substantially improves the design of valve-less pulse combustors also known as pulse jet engines. Compared to operating a traditional single combustor or two uncoupled pulse jet engines, the new design and method of operating pulse combustors produce less noise and vibration. This, in turn, enables a variety of practical applications in aircraft propulsion and other fields. North American Wave Engine Corporation won the Phase 1 Technology Validation award from TEDCO’s Maryland Innovation Initiative Commercialization Program to demonstrate the utility of the technology for a specific commercial application.

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    Category:Aerospace

    Established:

  • Aeroseed, LLC

    Aeroseed, LLC has a license to an advanced micro-scale vertical flyer. The flyer’s unique maple seed shaped wing design permits it to maneuver omnidirectionally with a 360 degree field of view camera, all while maintaining an extremely small visible airborne footprint. The micro-air vehicle (MAV) technology is controllable from long distances (up to 1.5 miles) and has been fitted with a simple payload. The flyer can be controlled using a traditional radio-frequency (RF) controller or an iPhone/iPad software application. 

    Category:Aerospace

    Established:

  • Streamlined Embedded Technologies, LLC Logo

    Streamlined Embedded Technologies, LLC

    Streamlined Embedded Technologies provides optimized signal processing solutions that enable deployment of advanced functionality for processing, communicating, and managing images, video streams, and various other forms of sensor data.

    Category:Power Electronics

    Established:

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