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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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‘Sashi’ Agar- Agar for the Specific Detection of Salmonella and Shigella
Published Sunday, November 12, 2006Researchers have developed a single plating agar that detects both Shigella and Salmonella species. Importantly, the new agar is capable of doing this with greater sensitivity and specificity, for both agents, than other agars in common use. The new agar, because of its ability to efficiently detect two major human pathogens, appears to...
Categories: Research Tools, Antibodies, & Reagents
Keyword(s): Microbiological media, agar, Salmonella, shigella
Docket: LS-2006-034
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Zona Incerta Stimulation for Chronic Pain Relief
Published Thursday, May 29, 2014Central pain syndrome (CPS) is a debilitating condition affecting with lesions or dysfunction in the central nervous system. CPS is a neurological disorder resulting from damage to or dysfunction of the pain-conducting pathways of the central nervous system. The patented invention describes a novel method for treating CPS regions of the...
Investigator(s): Asef Keller, Raimi Quiton, Peter Murray, Radi Masri, Jessica Lucas
Categories: Devices, Methods of Treatment
Keyword(s): chronic, pain, device, neurostimulation
Docket: AK-2009-044
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ZAP-70 As Biomarker and Immune System Modulator
Published Thursday, May 29, 2014The body's immune system is characterized by its ability to rapidly respond to foreign antigens (part of a bacterial or cancer cell, for example) that were previously encountered. This rapid response is mediated by memory T lymphocytes. When these cells are activated, they produce effector cytokines, such as TNF-alpha and IFN-gamma, which...
Investigator(s): Donna Farber, Francesca Okoye, Meena Chandok
Keyword(s): immune system, T cell, biomarker
Docket: DF-2008-006
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Xv1 Inhibition As A Novel Antimitotic Cancer Therapy
Published Thursday, July 7, 2022Mitosis has been an attractive target for anti-cancer therapies given that uncontrolled cell division is one of the key hallmarks of cancer. However, some normal cells like hematopoietic progenitor cells (HPCs), also undergo rapid cell division. Therefore, nearly all current cell cycle-targeted drugs are limited by their severe toxicity to such...
Investigator(s): Shengyun Fang, Yongwang Zhong
Keyword(s): cancer, Cancer Therapy, Targeted Therapy, XBP1, Xv1
Docket: SF-2020-011
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World’s Highest Energy Density Thin Film Battery
Published Tuesday, June 2, 2009The market for thin film batteries is projected for explosive growth in the coming years. Thin film batteries are enabling the proliferation of electronic devices in ubiquitous applications not possible before, including wireless sensor networks, active RFID, wearable electronics, and medical devices. Conventional battery technologies have...
Categories: Power Electronics, Materials, Engineering
Keyword(s): flexible high energy density rechargeable battery solar harvesting
Docket: PS-2008-041
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World Gas Model
Published Thursday, January 7, 2010The World Gas Model, developed at the University of Maryland, offers an in-depth, interactive model of global natural gas markets unmatched in scope and depth of information. Features of the software include- coverage of 95% of worldwide natural gas production- inclusion of 73 production and 75 consumption countries- use of...
Categories: Software + Algorithm
Keyword(s): model, gas, natural gas, energy, market, game theory
Docket: IS-2009-045
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Wnt Signaling Pathway Inhibitors for Treatments of Disease
Published Wednesday, May 17, 2023Summary UMB inventors have developed compounds that inhibit the Wnt/β-catenin signaling pathway, which is implicated in various diseases, including cancer and metabolic disorders such as type 2 diabetes, obesity,...
Investigator(s): Fengtian Xue, Yan Shu
Categories: Therapeutics, Small molecules, Methods of Treatment
Keyword(s): cancer, Metabolic Disease, diabetes
Docket: FX-2015-082
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Wnt Signaling Inhibitors for the Treatment of Diabetes
Published Tuesday, December 12, 2017The Wnt/β-catenin signaling pathway plays a pivotal role in cell proliferation and differentiation through the regulation of the transcriptional factor β-catenin. The Wnt pathway has been studied extensively for cancer (colon, liver) but the role of the Wnt...
Investigator(s): Fengtian Xue, Yan Shu
Keyword(s): Metabolic Disease, diabetes, small molecule inhibitor
Docket: FX-2015-082
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Wireless Power Transfer Using Superconducting Oscillators
Published Monday, December 7, 2015The field of non-radiative modes of coupled resonance used for wireless power transfer has been of great recent interest. The transfer of energy over non-negligible distances has the advantage of being impervious to extraneous environmental objects, e.g., ferrous materials. Existing resonant inductive power transfer has provided a transfer of 60...
Categories: Power Electronics
Keyword(s): wireless power, power transfer
Docket: PS-2009-050
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Wing Pitch Angle Control Device
Published Sunday, November 12, 2006A wing using this invention is distinctly different from other wings that have been made in that it is completely self contained, solid state, and requires no actuators inside the fuselage. A torque plate allows it to be stowed and extended without the complication of mechanical linkages. Also, the use of low-cost actuator materials may bring...
Keyword(s): wing, actuator, torque plate, missle, fuselage,
Docket: UM-92-028