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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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ANALYTE-SENSITIVE PROBES AND CONTACT LENS FOR DIAGNOSIS OF OCULAR PATHOLOGIES
Published Thursday, November 9, 2023Summary The patent introduces a contact lens integrated with analyte-sensitive probes for diagnosing ocular pathologies through the detection of specific analytes in basal tears. This non-invasive, real-time monitoring technology has applications in medical diagnostics and...
Investigator(s): Joseph R. Lakowicz, Ramachandram Badugu, E. Albert Reece
Categories: Devices, Imaging devices, Diagnostics, Imaging, Healthcare
Keyword(s): Analyte-sensitive probes, fluorescence, Diagnostics, Real-time monitoring
Docket: JL-2019-091
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Silicone Hydrogel Based Fluorescent Assay and Contact Lens
Published Wednesday, November 8, 2023Summary The "Silicone Hydrogel Based Fluorescent Assay and Contact Lens" patent introduces a novel technology for non-invasive medical diagnostics. It integrates a fluorescent assay into a silicone hydrogel contact lens, enabling real-time glucose monitoring in tear fluid. This...
Investigator(s): Joseph R. Lakowicz, Ramachandram Badugu, E. Albert Reece
Categories: Devices, Diagnostics, Biomarker
Keyword(s): fluorescent assay, Glucose Monitoring, analyte detection, biomarker monitoring, diabetes
Docket: JL-2016-128
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Real Time in-situ Monitoring of Drug Product Degradation Using Water Proton NMR
Published Wednesday, May 17, 2023Summary This technology uses NMR spectroscopy to measure changes in the NMR signal of water, which is sensitive to changes in the chemical environment of the drug molecules it interacts with. This patented method allows for...
Investigator(s): Bruce Yu, Marc Taraban, Katharine Briggs
Categories: Devices, Diagnostics, Therapeutics, Small molecules, Biologics, Vaccines, Vaccine, Other
Keyword(s): NMR, Quality Control, vaccine, Drug Manufacturing, Freeze-Thaw
Docket: BY-2020-079
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Noninvasive Quantitation of Full Versus Empty Capsids Using Water Proton NMR
Published Wednesday, May 17, 2023Summary This invention proposes a method for using NMR relaxation rates to determine whether capsid preparations contain empty or full viral capsids and to quantify the capsid content of the preparation....
Investigator(s): Bruce Yu, Marc Taraban
Categories: Devices, Diagnostics, Therapeutics, Small molecules, Biologics, Vaccines, Vaccine, Other
Keyword(s): NMR, Quality Control, vaccine, Drug Manufacturing, Freeze Thaw
Docket: BY-2020-059
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System and Method for Diagnosis, Monitoring, and Treatment of Obstructive Sleep Apnea
Published Monday, September 30, 2019Sleep Apnea treatment represents a $6 billion market in the United States. Current treatment methods suffer from poor compliance rates. The inventors have proposed a novel ultrasound device to diagnose and treat sleep apnea.
Investigator(s): Amal Isaiah, Jeffrey Wolf
Categories: Devices, Imaging devices, Diagnostics, Imaging, Methods of Treatment
Keyword(s): sleep apnea
Docket: AI-2018-039
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Methods and Apparatus for Cuffless Blood Pressure Measurement
Published Monday, June 20, 2016Background:Hypertension affects ¼ of the world’s population and is a major risk factor for stroke and heart attack – two world leading causes of death. Current hypertension diagnostic resides in-clinic and is performed by the patient’s physician. With roughly 20% of hypertension patients not knowing they have it, and due to high...
Categories: Devices, Diagnostics, Bioengineering, Software + Algorithm
Keyword(s): blood pressure, hypertension, Smartphone
Docket: PS-2016-001
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Portable Multi-Parameter Cancer Diagnostic Device
Published Sunday, May 17, 2015Background: Each year in USA alone, more than 200,000 breast cancer cases are diagnosed. The transformation from benign to cancerous state changes the morphological signatures in the tumor environment. Mechanical and electrical phenotyping has been demonstrated as a promising technique to study the progression of the breast cancer. Thus, a...
Categories: Diagnostics, Platforms, Devices
Keyword(s): breast cancer, Cancer Diagnosis
Docket: PS-2015-017
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Microdevice for the Detection of Sequence Differences in Biological Samples
Published Tuesday, November 4, 2014BackgroundWith the advancements in biomedical research, accurate sequencing of biological samples is becoming of greater importance. The completion of the Human Genome Project has highlighted the potential of single nucleotide polymorphisms (SNPs) in DNA while the increase in protein-based therapies has increased interest in the...
Categories: Diagnostics, Devices, Research Tools, Antibodies, & Reagents
Keyword(s): Gene sequencing, protein sequencing, lab-on-chip
Docket: LS-2014-076