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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Dialysis Driven Real-Time PCR with Surface Enhanced Raman Spectroscopy in a Thermoplastic Chip
Published Thursday, September 27, 2018BackgroundOver the past decade, there has been a push for the use of microfluidic devices as ideal point of care of diagnostic tools as a result of their portability and simplicity. These devices allow for the manipulation of small volumes of liquid in microfabricated channels thereby, facilitating the analyses of disease biomarkers such...
Keyword(s): 525
Docket: PS-2017-153
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Membrane Displacement Traps for Droplet Discretization and Manipulation
Published Thursday, September 27, 2018BackgroundMicrofluidics is a class of technology where the precise manipulation of fluids in very small channels and devices leads to improved devices in fields as different as medical diagnoses and inkjet printing. A subclass of microfluidic technology is Droplet-based Microfluidics where instead of manipulating a continuous flow,...
Keyword(s): 525
Docket: PS-2017-121
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Confidence-Based Robotic Surgery
Published Monday, September 24, 2018Robotic assisted surgery (RAS) was mainly developed to facilitate minimal invasive surgery by leveraging on the dexterity and precision of programmed tools. The features of this technology allow for smaller incisions, shorter hospital stays and faster wound healing, these benefits being very popular amongst patients, surgeons and insurance...
Keyword(s): Robotic assisted Surgery, Shared control
Docket: PS-2018-056
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Novel Compounds for Anti-Giardiasis and Anti-Amoebiasis Treatment
Published Tuesday, August 21, 2018Background Amoebiasis and Giardiasis are enteric diseases caused by protozoan parasites, Entamoeba histolytica and Giardia lamblia respectively. Symptoms include diarrhea and severe loss of absorption of nutrients. Current frontline treatments, nitroimidazoles and thiazolides, are plagued not only by side effects but also increased likelihood...
Keyword(s): 525
Docket: LS-2017-033
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A Reliable, High-Yield Method to Grow Uniform Epitaxial Graphene Precursor Layer on SiC
Published Tuesday, July 17, 2018Background:The global market for graphene based products is projected to be 2 billion dollars after the year 2020 at an annual growth rate of 46.3 %. This trend is mainly attributable to graphene’s unique combination of electrical, optical, and mechanical properties, which makes it a top contender for ultra-small, ultra-fast electronics...
Keyword(s): Epitaxial graphene
Docket: PS-2018-015
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An Improved Avian Influenza Vaccine for New Born Chicks
Published Sunday, July 8, 2018Background Avian influenza Virus (AIV) outbreaks not only cause the decimation of broiler and egg-laying chicken populations at once but also result a close to 50% increase in the price of poultry meat and eggs, thereby impacting the end consumer as well. Currently, effective vaccines against AIV are not available. AIV outbreaks are...
Keyword(s): 525
Docket: LS-2017-075
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QUIS™ (Questionnaire for User Interaction Satisfaction)
Published Thursday, July 5, 2018The QUIS™ is an instrument which evaluates user satisfaction with the human-computer interface aspect of other software packages and computer systems. It has been standardized over a number of applications and research studies. The QUIS™ assesses six factors of overall reactions to a system and 21 components which contribute to usability...
Keyword(s): Software development tools (3SOF300), Human computer interaction software (3SOF310)
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Predicting Success of Pharmaceuticals for Cancer Treatments via Synthetic Rescues
Published Thursday, May 24, 2018A framework that tracks resistance to cancer treatments to predict the likelihood of success in the treatment of cancer in individual patients. The framework can be used to decide the best method of treatment for patients and can also be applied to developing new forms of cancer treatment and refining the design of already existing treatments that...
Keyword(s): bioinformatics, cancer, cancer treatment, synthetic rescues, resistance
Docket: IS-2015-119
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Sailfish - A System for Estimating Gene Expression from RNA-Seq Reads
Published Thursday, May 3, 2018Sailfish implements an efficient, accelerated expectation-maximization algorithm for quantifying isoform abundance that produces high-quality results, and is capable of correcting numerous types of systematic bias that are known to occur in RNA-seq experiments. In the paper, we demonstrate that, on both real and synthetic data, Sailfish is as...
Categories: Software + Algorithm
Keyword(s): RNA, Gene Expression, estimation, open, source
Docket: IS-2017-155
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An Easy-to-Deploy Temporal Thermographic Data Collection and Analysis System
Published Thursday, May 3, 2018Buildings in the United States consume a significant amount of energy and release an increasing amount of CO2. Accordingly, tools and techniques have been developed to determine where energy efficiency in buildings can be improved. One such technique is thermography, where auditors determine energy inefficiency using a thermal camera that shows...
Categories: Software + Algorithm, Information Technology
Keyword(s): temporal, thermography, visualization, energy, efficiency
Docket: PS-2017-069