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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Surrogate-Based Prediction Model for Real-Time Tumor Monitoring during Radiotherapy
Published Friday, March 31, 2017To ensure tumor-targeting accuracy over the course of radiation treatment while minimizing the dosimetric impact to healthy tissue, respiratory surrogate models are utilized to monitor tumor position while compensating for tumor motion. These models are developed from a training dataset of concurrent tumor positions and...
Investigator(s): Warren D’Souza PhD
Categories: Software + Algorithm, Healthcare, Methods of Treatment
Keyword(s): radiology; medical imaging; image-guided radiation therapy
Docket: WD-2010-069
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Individually Optimized Uniform Enhancement in Contrast Enhanced Computed Tomography (CT) Scans
Published Thursday, February 23, 2017CT has become the primary method for to evaluate for pulmonary embolism (PE). However for CT to be diagnostic, uniform contrast enhancement of the pulmonary arterial tree is desired. Obtaining uniform contrast enhancement is difficult because there are numerous factors involved. There are methods for calculating the correct injection rate for...
Investigator(s): Ming Xue, Hao Howard Zhang, Seth Kligerman, Warren D. D’Souza, Wei Lu, Wookjin Choi
Categories: Software + Algorithm
Keyword(s): radiology
Docket: MX-2013-110
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Motion Artifact Suppression in 4D CT Reconstruction with Iterative Back Projection
Published Thursday, October 15, 2015Computational tomography (CT) is computer-aided reconstruction imaging of X-ray projection data and is commonly used for diagnostic purposes. Although image quality is essential for diagnostic accuracy, CT images are prone to artifacts because the image is reconstructed using multiple measurements and a single error in...
Investigator(s): Byong Yong Yi, Nilesh Mistry, Cedric X Yu, Giovanni Lasio
Categories: Imaging devices, Software + Algorithm
Docket: BY-2014-089
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Method for Image Reconstruction of Moving Radionuclide Source Distributions
Published Monday, September 28, 2015Positron emission tomography (PET) is a functional imaging technique for studying biological processes in vivo for pre-clinical and clinical studies. PET compounds labelled with short-lived positron emitters are delivered to a subject (human, animals or plants). The raw PET scanning data is reconstructed...
Investigator(s): Mark Smith
Categories: Imaging, Software + Algorithm, Other
Keyword(s): PET, SPECT, Image reconstruction, nuclear medicine
Docket: MS-2009-091
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An Automated Medical Student Performance Evaluation Software
Published Friday, September 26, 2014In the United States and Canada, a Medical Student Performance Evaluation (MSPE) is required as part of a medical student’s residency application. The MSPE includes specific information from the student’s academic record including both didactic and clinical courses. The Automated Student Affairs Processes (ASAP) is a user-friendly, platform...
Investigator(s): Kevin Brown, Priyanka Koneru, Sara Menso
Categories: Platforms, Software + Algorithm, Information Technology, Education/Training/Multimedia
Keyword(s): MSPE, software, medical school, administrative office, medical admissions
Docket: KB-2014-002
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University of Maryland, School of Dentistry OSCE Exam
Published Thursday, May 29, 2014Objective Structures Clinical Exams (OSCEs) are used in the assessment of health sciences professionals (e.g. orthoptics, optometry, medicine, nursing, pharmacy) to test clinical performance and competence in skills such as communication, clinical examination, medical procedures, prescription writing, radiographic...
Investigator(s): Judith A Porter, Doug Brotherton, Shabrez Ahmed, Karen Faraone, Edward G Grace, Cynthia L Idzik-Starr, Andrea M Morgan, Harlan Shiau
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): dental, clinical, exams
Docket: JP-2012-099
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Techniques for Converting Analog Medical Video to Digital Objects
Published Thursday, May 29, 2014The present invention relates to converting analog medical video data to a digital object that associates descriptive data with the video, and in particular, to forming digital imaging and communications in medicine (DICOM) objects from analog medical video data in a legacy data collection system.
Investigator(s): Paul Nagy
Categories: Software + Algorithm, Healthcare
Keyword(s): medical, video, digital
Docket: PN-2006-047
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Techniques for Implementing a Virtual Patient
Published Thursday, May 29, 2014Medical care delivery is a major industry in the United States. An important component of medical care delivery is a cadre of trained medical care professionals who can diagnose patient conditions and prescribe treatment protocols using cognitive skills. The fewer errors made by this cadre, the better the overall quality of medical care is...
Investigator(s): Bruce Jarrell, Sergei Nirenburg, Joan Marjorie McShane, Stephen Beale
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): training, virtual, patient
Docket: BJ-2006-061
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SILCS: Site Identification by Ligand Competitive Saturation. Method for binding site identification by molecular dynamics simulation
Published Thursday, May 29, 2014The present invention is directed to a method of computational chemistry for identifying binding sites by molecular dynamics simulations using ligand competitive saturation. Fragment-based drug discovery relies on a simple premise: identify small molecule fragments that bind to a target region of a large molecule and then evolve or link the...
Investigator(s): Alex MacKerell Jr., Olgun Guvench
Categories: Research Tools, Antibodies, & Reagents, Software + Algorithm
Keyword(s): simulation, drug design
Docket: AM-2009-054
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Radiology Protocoler
Published Thursday, May 29, 2014The Radiology Protocoler is a centralized, web-based system for automatically tracking, editing, and storing existing medical radiology documents and files both automatically and on demand. The web-based design allows the system to be accessed from within a hospital, radiology practice, or through a virtual private network (VPN). Modularity...
Investigator(s): Ross Filice, Wayne LaBelle
Categories: Software + Algorithm
Keyword(s): radiology, software
Docket: RF-2010-078