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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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SILCS: Site Identification by Ligand Competitive Saturation. Method for binding site identification by molecular dynamics simulation
Published Thursday, May 29, 2014The present invention is directed to a method of computational chemistry for identifying binding sites by molecular dynamics simulations using ligand competitive saturation. Fragment-based drug discovery relies on a simple premise: identify small molecule fragments that bind to a target region of a large molecule and then evolve or link the...
Investigator(s): Alex MacKerell Jr., Olgun Guvench
Categories: Research Tools, Antibodies, & Reagents, Software + Algorithm
Keyword(s): simulation, drug design
Docket: AM-2009-054
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Techniques for Implementing a Virtual Patient
Published Thursday, May 29, 2014Medical care delivery is a major industry in the United States. An important component of medical care delivery is a cadre of trained medical care professionals who can diagnose patient conditions and prescribe treatment protocols using cognitive skills. The fewer errors made by this cadre, the better the overall quality of medical care is...
Investigator(s): Bruce Jarrell, Sergei Nirenburg, Joan Marjorie McShane, Stephen Beale
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): training, virtual, patient
Docket: BJ-2006-061
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Techniques for Converting Analog Medical Video to Digital Objects
Published Thursday, May 29, 2014The present invention relates to converting analog medical video data to a digital object that associates descriptive data with the video, and in particular, to forming digital imaging and communications in medicine (DICOM) objects from analog medical video data in a legacy data collection system.
Investigator(s): Paul Nagy
Categories: Software + Algorithm, Healthcare
Keyword(s): medical, video, digital
Docket: PN-2006-047
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University of Maryland, School of Dentistry OSCE Exam
Published Thursday, May 29, 2014Objective Structures Clinical Exams (OSCEs) are used in the assessment of health sciences professionals (e.g. orthoptics, optometry, medicine, nursing, pharmacy) to test clinical performance and competence in skills such as communication, clinical examination, medical procedures, prescription writing, radiographic...
Investigator(s): Judith A Porter, Doug Brotherton, Shabrez Ahmed, Karen Faraone, Edward G Grace, Cynthia L Idzik-Starr, Andrea M Morgan, Harlan Shiau
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): dental, clinical, exams
Docket: JP-2012-099
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Methods for prediction of subject-specific hemodynamic response to vasopressors
Published Sunday, June 29, 2014BackgroundVasopressors are medications that raise blood pressure in a patient, which helps increase blood flow to peripheral tissues. Vasopressors are commonly used to treat patients who have a body wide reduction in blood circulation. Currently, vasopressors are administered manually by clinicians, who typically adjust dosage iteratively...
Categories: Healthcare, Software + Algorithm, Surgical devices
Keyword(s): vasopressor infusion, dosage, cardinal parameter, peripheral resistance, medical device, epinephrine
Docket: IS-2013-086
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Compressive Radar Imaging Technology
Published Sunday, June 29, 2014The military utilizes the mapping of targets and terrain to provide much needed information for its field operations. Synthetic Aperture Radar (SAR) has been used in this capacity to provide a quality map for these operations. Researchers in the Department of Electrical and Computer Engineering at the University of Maryland–College...
Categories: Software + Algorithm, Aerospace, Engineering
Keyword(s): defense, radar, compressed imaging, mapping, environmental monitoring
Docket: IS-2009-018
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A Method of Matrix Spectral Factorization
Published Sunday, June 29, 2014BackgroundSpectral factorization is a method of reducing a matrix of a high order dimension into a series of smaller matrices to perform more efficient computations. Spectral factorization has broad applications, including signal and image filtering, control systems, data processing, and data compression. However, spectral factorization...
Categories: Software + Algorithm
Keyword(s): signal processing, matrices, data compression
Docket: IS-2008-049
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An Automated Medical Student Performance Evaluation Software
Published Friday, September 26, 2014In the United States and Canada, a Medical Student Performance Evaluation (MSPE) is required as part of a medical student’s residency application. The MSPE includes specific information from the student’s academic record including both didactic and clinical courses. The Automated Student Affairs Processes (ASAP) is a user-friendly, platform...
Investigator(s): Kevin Brown, Priyanka Koneru, Sara Menso
Categories: Platforms, Software + Algorithm, Information Technology, Education/Training/Multimedia
Keyword(s): MSPE, software, medical school, administrative office, medical admissions
Docket: KB-2014-002
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Efficient Mechanisms for Thread Handling in Multithreaded Computer Systems
Published Tuesday, November 11, 2014During the 1980s and the early 1990s, quite a few very talented computer science researchers worked on the following problem: Seek the "ultimate" parallel programming model that will allow easy expression of parallel algorithms and their programs in the model, as well as validation of the model by algorithmic paradigms and solutions for as many...
Categories: Information Technology, Software + Algorithm
Keyword(s): parallel computing, multithreading, SIMD, threading, algorithms
Docket: IS-2006-005
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Improving Smartphone Battery Life with Cooperative Relaying on LTE Networks
Published Monday, July 13, 2015BackgroundAs smartphones, tablets, and other mobile devices have become more powerful and cheaper, devices that communicate through cellular networks have become prevalent, if not ubiquitous. However, the utility of these devices are limited by battery life, which has grown at a much slower pace than processing capability, and data...
Categories: Software + Algorithm, Information Technology, Clean Technology, Clean Tech
Keyword(s): 525
Docket: IS-2014-170