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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Method for Image Reconstruction of Moving Radionuclide Source Distributions
Published Monday, September 28, 2015Positron emission tomography (PET) is a functional imaging technique for studying biological processes in vivo for pre-clinical and clinical studies. PET compounds labelled with short-lived positron emitters are delivered to a subject (human, animals or plants). The raw PET scanning data is reconstructed...
Investigator(s): Mark Smith
Categories: Imaging, Software + Algorithm, Other
Keyword(s): PET, SPECT, Image reconstruction, nuclear medicine
Docket: MS-2009-091
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Motion Artifact Suppression in 4D CT Reconstruction with Iterative Back Projection
Published Thursday, October 15, 2015Computational tomography (CT) is computer-aided reconstruction imaging of X-ray projection data and is commonly used for diagnostic purposes. Although image quality is essential for diagnostic accuracy, CT images are prone to artifacts because the image is reconstructed using multiple measurements and a single error in...
Investigator(s): Byong Yong Yi, Nilesh Mistry, Cedric X Yu, Giovanni Lasio
Categories: Imaging devices, Software + Algorithm
Docket: BY-2014-089
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Methods and Apparatus for Cuffless Blood Pressure Measurement
Published Monday, June 20, 2016Background:Hypertension affects ¼ of the world’s population and is a major risk factor for stroke and heart attack – two world leading causes of death. Current hypertension diagnostic resides in-clinic and is performed by the patient’s physician. With roughly 20% of hypertension patients not knowing they have it, and due to high...
Categories: Devices, Diagnostics, Bioengineering, Software + Algorithm
Keyword(s): blood pressure, hypertension, Smartphone
Docket: PS-2016-001
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Method of Optimal Data Repair in Distributed Storage
Published Wednesday, July 13, 2016Distributed storage systems are widely used for data storage, with applications ranging from social networks to file and video sharing. Currently deployed systems are formed of thousands of individual drives (nodes), and drive failures occur on a daily basis. For this reason, companies utilizing or providing distributed storage solutions have...
Categories: Engineering, Software + Algorithm
Keyword(s): data repair; distributed storage; data storage; file sharing; video sharing
Docket: IS-2016-020
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Joint Optimization for Social Content Delivery in Heterogeneous Wireless Networks
Published Thursday, August 4, 2016Social networks such as Facebook, Twitter, Google+ and others use their users’ profiles to recommend content. Relevance of the recommended content to the user is extremely important as it determines the quality of user experience, and thus user’s willingness to continue to utilize the network. Another important factor of user experience is...
Categories: Software + Algorithm, Information Technology
Keyword(s): wireless, content delivery, wireless networks, social networks
Docket: IS-2016-056
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Joint Optimization for Social Content Delivery in Wireless Networks
Published Thursday, August 4, 2016BackgroundSocial networks such as Facebook, Twitter, Google+ and others use their users’ profiles to recommend content. Relevance of the recommended content to the user is extremely important as it determines the quality of user experience, and thus user’s willingness to continue to utilize the network. Another important factor of user...
Categories: Software + Algorithm, Information Technology
Keyword(s): 525
Docket: IS-2016-055
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Simetric
Published Monday, December 19, 2016BackgroundChildren undergoing medical procedures experience stressful reactions that can impair treatment and recovery. Currently, hospitals employ various methods to reassure these children, including showing them the treatment room and talking them through the procedure. However, some hospitals lack the necessary resources to accomplish...
Categories: Software + Algorithm, Engineering
Keyword(s): virtual reality, procedure, stress, anxiety, treatment
Docket: IS-2016-073
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Individually Optimized Uniform Enhancement in Contrast Enhanced Computed Tomography (CT) Scans
Published Thursday, February 23, 2017CT has become the primary method for to evaluate for pulmonary embolism (PE). However for CT to be diagnostic, uniform contrast enhancement of the pulmonary arterial tree is desired. Obtaining uniform contrast enhancement is difficult because there are numerous factors involved. There are methods for calculating the correct injection rate for...
Investigator(s): Ming Xue, Hao Howard Zhang, Seth Kligerman, Warren D. D’Souza, Wei Lu, Wookjin Choi
Categories: Software + Algorithm
Keyword(s): radiology
Docket: MX-2013-110
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Surrogate-Based Prediction Model for Real-Time Tumor Monitoring during Radiotherapy
Published Friday, March 31, 2017To ensure tumor-targeting accuracy over the course of radiation treatment while minimizing the dosimetric impact to healthy tissue, respiratory surrogate models are utilized to monitor tumor position while compensating for tumor motion. These models are developed from a training dataset of concurrent tumor positions and...
Investigator(s): Warren D’Souza PhD
Categories: Software + Algorithm, Healthcare, Methods of Treatment
Keyword(s): radiology; medical imaging; image-guided radiation therapy
Docket: WD-2010-069
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Combination Assessment of Volume Status (CAVS)
Published Wednesday, May 17, 2023Early and aggressive fluid resuscitation in shock is associated with improved patient outcome and mortality. However, there is a clear correlation between cumulative fluid balance and mortality. There is, therefore, a benefit to adopting a systematic approach to fluid resuscitation to determine which patients would benefit from a fluid bolus...
Investigator(s): Sarah Murthi
Categories: Diagnostics, Software + Algorithm
Keyword(s): CAVS, shock, ultrasound, POCUS
Docket: SM-2016-067