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Assessing Biopharmaceutical Aggregation Using Magnetic Resonance Relaxometry
Published Tuesday, May 27, 2014Aggregation is a significant problem in biopharmaceutical manufacturing and long-term storage, as aggregated proteins may lose their biological activities, alter concentration, distribution, and kinetics, and aggravate immunogenicity. As the number of biomacromolecule-based, nanoparticle-conjugated, and non-biological...
Investigator(s): Yihua Bruce Yu, Marc Taraban, Yue Feng
Categories: Other
Keyword(s): Quality Control, Biopharmaceutical, diagnostic
Docket: BY-2013-101