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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Functional Myelination of Neurons
Published Tuesday, May 7, 2024Summary This invention is a significant advancement in regenerative medicine, offering a novel stem cell-based therapy for demyelinating diseases. It utilizes melanocyte stem cells (MeSCs) from the skin to differentiate into cells capable of myelination, addressing diseases like...
Investigator(s): Thomas Hornyak and Sandeep Joshi
Categories: Therapeutics, Biologics, Stem Cells, Methods of Treatment
Docket: TH-2015-020
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Treating Optic Nerve Diseases with Neural Stem Cell Factors
Published Thursday, July 30, 2020The optic nerve lamina region (ONLR) is a small junctional region between the eye and optic nerve (ON), and is the primary damage site in age-related eye diseases, such as open angle glaucoma (OAG). Dr. Bernstein’s group at UMB discovered that the ONLR of both human and rodent contains an adult neural progenitor cell (NPC) niche, which...
Investigator(s): Steven Bernstein; Candace Kerr; Sally Temple
Categories: Therapeutics, Stem Cells
Keyword(s): Stem cell; eye disease; glaucoma
Docket: SB-2015-057
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Pluripotent Stem Cell Production Method
Published Wednesday, May 28, 2014One of the major hurdles in stem cell research is that techniques for purification and propagation can be tedious and result in low yields. Standard methods require feeder cells, matrix, and serum, which are expensive and can introduce contaminants. UMB researchers, however, have developed an alternative method to consistently and reliably...
Investigator(s): G. David Trisler, Bernard M. Pessac, Christopher T. Bever Jr., James E. Goolsby
Categories: Research Tools, Antibodies, & Reagents, Therapeutics, Stem Cells
Keyword(s): stem cell
Docket: GT-2004-009