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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Real Time in-situ Monitoring of Drug Product Degradation Using Water Proton NMR
Published Wednesday, May 17, 2023Summary This technology uses NMR spectroscopy to measure changes in the NMR signal of water, which is sensitive to changes in the chemical environment of the drug molecules it interacts with. This patented method allows for...
Investigator(s): Bruce Yu, Marc Taraban, Katharine Briggs
Categories: Devices, Diagnostics, Therapeutics, Small molecules, Biologics, Vaccines, Vaccine, Other
Keyword(s): NMR, Quality Control, vaccine, Drug Manufacturing, Freeze-Thaw
Docket: BY-2020-079
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Noninvasive Quantitation of Full Versus Empty Capsids Using Water Proton NMR
Published Wednesday, May 17, 2023Summary This invention proposes a method for using NMR relaxation rates to determine whether capsid preparations contain empty or full viral capsids and to quantify the capsid content of the preparation....
Investigator(s): Bruce Yu, Marc Taraban
Categories: Devices, Diagnostics, Therapeutics, Small molecules, Biologics, Vaccines, Vaccine, Other
Keyword(s): NMR, Quality Control, vaccine, Drug Manufacturing, Freeze Thaw
Docket: BY-2020-059
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In situ determination of alum filling evenness and sedimentation in pharmaceutical products using water NMR
Published Wednesday, May 17, 2023Summary The invention describes a fast and non-destructive technique to determine the evenness of alum particle filling levels and/or...
Investigator(s): Bruce Yu, Christopher Fox, Marc Taraban
Categories: Diagnostics, Vaccine, Other
Keyword(s): NMR, Quality Control, vaccine, Drug Manufacturing
Docket: BY-2019-021
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Solvent nuclear magnetic resonance for noninvasive inspection of particle-containing products
Published Wednesday, May 17, 2023Summary This patented technology uses solvent nuclear magnetic resonance (NMR) as a noninvasive method for quality control testing of particle products in both pharmaceuticals and non-pharmaceuticals. This technique is rapid,...
Investigator(s): Bruce Yu, Marc Taraban
Categories: Diagnostics, Industrial Processing, Other
Keyword(s): NMR, Pharmaceutical, food, nanoparticles, Quality Control, Counterfeit Detection
Docket: BY-2017-009