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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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1-THP/LDN (low dose Naltrexone) combination as medication for substance dependence disorder
Published Tuesday, May 27, 2014Addiction is a complex and costly disorder that is difficult to treat due to the effects on multiple brain circuits involved in reward and motivation, learning and memory, and inhibitory control over behavior(s). Treatment options remain limited and addiction to alcohol and illicit drugs cause significant problems and economic burden on society...
Investigator(s): Jia Bei Wang, Sarah Sushchyk
Categories: Therapeutics
Keyword(s): Naltrexone
Docket: JW-2012-106
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3D Face Modeling From Video
Published Sunday, March 7, 2004Researchers at the University of Maryland have developing techniques for reconstruction three-dimensional (3D) models from a sequence of two-dimensional (2D) images. More particularly their invention is directed to reconstruction 3D models of an object from 2D video sequences taken from the object. The object may be the features of a living object...
Categories: Information Technology
Keyword(s): face recognition, video, 3D, homeland
Docket: IS-2002-046
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3D Printed Molds for 3D Tissue Culture Scaffolds
Published Tuesday, November 4, 2014BackgroundCellular and tissue culture is an important aspect of biological research. Having specific cell or tissue types in a controlled environment allows for development and refinement of the efficacy and safety of biological treatments. However, as researchers study more complex conditions, standard monolayer (2D) cell culture is...
Categories: Biological, Research Tools, Antibodies, & Reagents
Keyword(s): PDMS, stem cells, cell culture, tissue culture
Docket: LS-2014-073
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A Battery of Monoclonal Antibodies for the Differentiation of Newcastle Disease Virus
Published Wednesday, May 13, 2009Newcastle Disease Virus (NDV) strains differ in pathogenicity and produce a wide continuum of clinical diseases in chickens ranging from mild respiratory distress to death. Isolates of NDV are currently classified according to virulence manifested in susceptible poultry: lentogenic (mild), mesogenic (modest), and velogenic (highly virulent)...
Keyword(s): 525
Docket: 02-87-030
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A Biodegradable and Less Toxic Alternative to Lead Removal From Water
Published Wednesday, April 12, 2017BackgroundThe World Health Organization (WHO) estimates that lead poisoning contributes to 0.6% of the global disease burden in terms of disability adjusted life years (DALYs). Food and drinking water are chief sources for lead poisoning, which can be remediated through elimination of lead use, improved monitoring, and preventive mechanisms...
Keyword(s): Lead-toxicity, pollution, water, Filtration, lead-poisoning, hydrogel, biodegradable, lead-removal
Docket: LS-2016-047
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A Counterfeit Detection Scheme using Paper Surfaces and Mobile Cameras
Published Tuesday, August 23, 2016BackgroundCounterfeiting is a world-wide problem affecting high value documents, high end consumer product labels, and other assets. Traditional anti-counterfeiting mechanisms heavily rely on visual examination of the document or product label and decision of a particular examiner. Recent technological solutions include optically capturing...
Keyword(s): counerfeit, document, paper, authentication, mobile platform, security
Docket: IS-2015-165
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A Data Visualization Tool to Explore Multidimensional Clinical Datasets
Published Monday, June 19, 2017WinnowTM is an innovative tool to efficiently sift through arrays of longitudinal data, identify patterns, generate hypotheses, and subject these hypotheses to rigorous statistical analysis. It has an intuitive, interactive and insightful platform- valuable to all...
Investigator(s): Lisa Shulman, MD ; Amitabh Varshney, PhD
Categories: Software + Algorithm, Healthcare, Information Technology, Genomics/Proteomics/Database
Keyword(s): Software; Algorithm; Healthcare; Information Technology; Data Analytics
Docket: LS-2017-024
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A Data-Bearing Approach for Pilot-Embedding in Space-Time Coded MIMO Systems
Published Sunday, November 12, 2006Multiple-input multiple-output (MIMO) communication systems provide prominent benefits to wireless communication due to high capacity and reliability they can offer.Researchers at the University of Maryland have designed an innovative pilot-embedding technique for space-time (ST) coded MIMO systems with affordable computational cost and...
Categories: Microelectronics, Information Technology
Keyword(s): Pilot embedding, ST Block code, Time Multiplexing, Code Multiplexing
Docket: IS-2005-051
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A Deformable Lung Motion Phantom
Published Friday, March 8, 2019Motion caused by patient breathing can limit the accuracy of the prescribed dose delivered during radiation therapy (RT) especially for cancers in the thorax and abdomen. Sophisticated respiratory motion prediction and real-time motion modeling have been clinically implemented to improve the accuracy and precision of the dose being delivered to...
Investigator(s): Amit Sawant, Maida Ranjbar, Pouya Sabouri, Carlo Repetto
Categories: Devices
Keyword(s): Radiation Oncology
Docket: AS-2018-044
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A Distributed Bandwidth Allocation and Transmission Coordination Method for Quality of Service Provision in Wireless Ad Hoc Networks
Published Monday, March 24, 2003In contrast to the centralized cellular communication model, ad hoc networks consist of small and inexpensive wireless routers that can form distributed all-wireless infrastructures on the fly. They are currently being considered as complements or alternatives for wireless broadband data access to existing 3G networks. Ad hoc networks can operate...
Categories: Microelectronics, Information Technology
Keyword(s): ad hoc networks, wireless network, cellular architectures, 3G networks, unlicensed bands, quality of service, scheduled access protocol, bandwidth allocation, transmission conflicts, homeland
Docket: IS-2002-072