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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Horus: An RF-Based Location Determination System
Published Tuesday, February 10, 2004Horus is an RF-based (radio frequency-based) location determination system capable of locating a user carrying an RF-based device. The system, through a probabilistic location determination technique and through advanced signal strength processing techniques, is highly accurate. Through clustering techniques the system requires low...
Categories: Microelectronics, Information Technology
Keyword(s): Rf-based, locator, mobile, telecommunication, Rf, location
Docket: IS-2003-022
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Nuclease Deficient RecBCD Enzyme
Published Monday, February 2, 2004Researchers at the University of Maryland have isolated a set of plasma borne genes that encode three forms of a bacterial enzyme that unwinds double-stranded DNA very rapidly and with high processivity. The enzyme is also a nuclease that breaks down one or both strands of the DNA. The researches have mutated the gene so that it lacks detectable...
Categories: Research Tools, Antibodies, & Reagents, Biologics
Keyword(s): nuclease, double-stranded DNA, mutation
Docket: LS-2003-060
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A Novel Target for Antiviral Therapeutics
Published Monday, February 2, 2004The propagation of many important viruses depends upon the availability of precise ratios of viral proteins as determined by the efficiency of programmed ribosomal frameshifting (PRF). Thus a better understanding of the molecular mechanisms underlying the control of PRF can contribute toward new targets for the rational design of antiviral...
Categories: Vaccines, Biologics
Keyword(s): antiviral, translational termination
Docket: LS-2003-049
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NoteLens: Rapid Note-Taking Tool
Published Monday, January 12, 2004NoteLens is a note-taking program for Windows PCs.NoteLens is a note-taking tool that is so fast, it lets you concentrate on your notes--not on the interface. You'll never spend time deciding where to store notes, where to save them, or how to name them. NoteLens takes care of that for you. With a lightning fast full-text indexing system...
Categories: Information Technology
Keyword(s): microsoft out look, notes, pda. smartphones, e-mail
Docket: IS-2003-096
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Navigation Using X-ray Sources
Published Monday, January 5, 2004Researchers at the University of Maryland, College Park, have developed a system and method for navigation utilizing sources of pulsed celestial radiation.The invention includes a mobile receiver for detecting pulsed radiation. The receiver is mounted onto a spacecraft, satellite, planetary rover or other terrestrial or non-terrestrial...
Categories: Imaging devices
Keyword(s): navigation, space, satellite, radiation, detecting, receiver
Docket: PS-2003-064
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A Method for Dynamically Creating and Maintaining Network Structure Based on Client Mobility
Published Sunday, December 7, 2003A local area network (LAN) is a collection of personal terminals, mainframes, and workstations coupled to a communication link within a distance of 300 meters. LANs have commonly tak en the form of wired networks which connect directly via cable to each point within the network. Recently, however, wired networks are being replaced with wireless...
Categories: Microelectronics, Information Technology
Keyword(s): local area network, LAN, switching, hand-off latencies, ad hoc mode, WLANS
Docket: IS-2003-078
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TTRAC: The Technology Transfer and Commercialization System
Published Wednesday, October 8, 2003The Technology Transfer and Commercialization System, TTRAC, is a comprehensive, enterprise-class system for tracking and maintaining information during the technology transfer cycle. Developed through years of experience in the Office of Technology Commercialization at the University of Maryland, TTRAC supports the needs of any technology...
Categories: Education/Training/Multimedia, Information Technology
Keyword(s): TTRAC, technology transfer, database, Filemaker
Docket: IS-2003-013
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Spanwise Slotted Rotor Tip
Published Wednesday, June 11, 2003During the descent of rotorcraft at low speed, typically upon approach to a landing site, the noise generated by rotor blade vortex interactions (BVI) becomes very loud.The impulsive nature of BVI noise is extremely fatiguing to passengers and crews, as well as being annoying to the population near the landing areas. Another implication...
Categories: Aerospace
Keyword(s): vortex swirl velocity, blade vortex interaction(BVI), slotted tip rotor blade
Docket: PS-2003-039
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Transporting Chloride Across Biological Membranes with Oligomers Bearing Secondary Amide Functionalities: Potential Antibiotics, Anti-cancer Agents and Therapeutics for Cystic Fibrosis
Published Wednesday, June 11, 2003Chloride is the most physiologically important anion and its transport across cell membranes is a crucial process for life. While many synthetic cation channels and carriers have been described, few compounds are known to transport anions across membranes. New anion transporters are critical for development of drugs to combat diseases involving...
Categories: Small molecules
Keyword(s): chloride, oligomers, cystic fibrosis
Docket: LS-2002-065
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Improved Live Attenuated Newcastle Disease Vaccine
Published Sunday, June 1, 2003Newcastle disease virus (NDV) causes highly contagious and fatal disease affecting all species of birds. Vaccination against the disease has been widely used to protect birds from contracting Newcastle disease. The most commonly used method of vaccination involves exposure of chickens to low virulence strains of NDV. The main disadvantage of the...
Categories: Vaccines
Keyword(s): Newcastle, NDV, birds, vaccine, genetics
Docket: LS-99-100