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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Microtube platform for the thermal automation of multi-step reactions
Published Wednesday, March 28, 2018BackgroundThe automation of laboratory processes generally leads to increased quality control, higher throughput, and reduced operating costs. In fact, the global market for products related to laboratory automation, specifically liquid handling, is projected to be $ 3.5 billion in 2019 at an annual growth rate of 8.3%. Diagnostic assays...
Categories: Chemical, Microfluidics, Diagnostics
Keyword(s): 525
Docket: PS-2017-134
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Methods and Apparatus for Cuffless Blood Pressure Measurement
Published Monday, June 20, 2016Background:Hypertension affects ¼ of the world’s population and is a major risk factor for stroke and heart attack – two world leading causes of death. Current hypertension diagnostic resides in-clinic and is performed by the patient’s physician. With roughly 20% of hypertension patients not knowing they have it, and due to high...
Categories: Devices, Diagnostics, Bioengineering, Software + Algorithm
Keyword(s): blood pressure, hypertension, Smartphone
Docket: PS-2016-001
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Portable Multi-Parameter Cancer Diagnostic Device
Published Sunday, May 17, 2015Background: Each year in USA alone, more than 200,000 breast cancer cases are diagnosed. The transformation from benign to cancerous state changes the morphological signatures in the tumor environment. Mechanical and electrical phenotyping has been demonstrated as a promising technique to study the progression of the breast cancer. Thus, a...
Categories: Diagnostics, Platforms, Devices
Keyword(s): breast cancer, Cancer Diagnosis
Docket: PS-2015-017
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Microdevice for the Detection of Sequence Differences in Biological Samples
Published Tuesday, November 4, 2014BackgroundWith the advancements in biomedical research, accurate sequencing of biological samples is becoming of greater importance. The completion of the Human Genome Project has highlighted the potential of single nucleotide polymorphisms (SNPs) in DNA while the increase in protein-based therapies has increased interest in the...
Categories: Diagnostics, Devices, Research Tools, Antibodies, & Reagents
Keyword(s): Gene sequencing, protein sequencing, lab-on-chip
Docket: LS-2014-076
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Noninvasive Aortic Blood Pressure Measurement for Prediction of Cardiovascular Disease Risk
Published Tuesday, May 27, 2014BackgroundCardiovascular disease (CVD) is the number one cause of death in the US and the world, with an estimated 32.8% of deaths in the US having cardiovascular (CV) related factors. Ailments such as hypertension, atherosclerosis, myocardial infarction (heart attacks), and heart failure are all related to CVD. There are many ways of...
Categories: Healthcare, Diagnostics
Keyword(s): Cadiovascular disease, clinical, blood pressure, healthcare, heart disease, medical device
Docket: IS-2013-088
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Novel Genetic Mutations Associated with Lactose Persistence in African and Middle Eastern Populations.
Published Monday, July 27, 2009In humans, lactose intolerance is caused by the inability to metabolize lactose, the main carbohydrate present in milk. In adults the ability to digest lactose declines rapidly after weaning because of decreasing levels of the enzyme lactase phlorozin hydrolase (LPH). LPH is predominantly expressed in the small intestine, where it hydrolyzes...
Categories: Diagnostics
Keyword(s): genetic mutation, dietary, health
Docket: LS-2006-101
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Borrelia Burgdorferi Genetic Markers for Lyme Disease Diagnostics
Published Thursday, April 16, 2009BackgroundDiagnosing Lyme disease is notoriously difficult for physicians and veterinarians. Available tests have improved significantly over the last few decades but still leave much room for increased accuracy of results. As the genetic design of Lyme disease pathogen Borrelia burgdorferi is more fully understood, diagnostic kits may be...
Categories: Diagnostics, Biomarker
Keyword(s): Lyme Disease, Borrelia burgdorferi, B. burgdorferi, vaccine, diagnostic markers
Docket: LS-2009-015