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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Selective Plating Medium for Isolation of Salmonella
Published Tuesday, April 30, 1996Researchers at the University of Maryland, Department of Veterinary Medicine, in collaboration with researchers from the USDA, have developed an agar-based plating medium for the isolation of Salmonella species. This medium has been repeatedly demonstrated to be superior to other media in isolating Salmonella from both clinical and environmental...
Keyword(s): Salmonella, Bacterial Growth Media, Veterinary Diagnostic (1AHV110)
Docket: UM-90-015
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Construction of a Strain of E. coli That Can be Used to Select DNA Methyltransferase Clones
Published Tuesday, April 30, 1996Escherichia coli contains several genes, designated mcrA, mcrB and mmr, that are able to destroy DNA that has been methylated at specific sequences. Currently identified known methylase-producing strains have limited commercial value due to their low levels of enzyme production. One solution is to cloning and overexpressing the methylase genes in...
Keyword(s): DNA Detection (1BIO200), Methyltransferase, Bacteria (1BIO020)
Docket: UM-88-002
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Structural Actuation and Sensing through Directional Attachment
Published Tuesday, April 30, 1996For a number of years, researchers have attempted to develop a real-time sensor/actuator for the aerospace and aeronautic industries. However, the previous attempts have not been successful in coupling the actuator/sensor in such a way that its behavior is anisotropic; a requirement for real-time control of the substrate. Intelligent actuation...
Keyword(s): Structural actuation, Smart structures (2ADV090), Aeronautics, homeland
Docket: UM-89-012
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Mouse Monoclonal Antibody (Mab) Against Ehrlichia Risticii
Published Tuesday, April 30, 1996Researchers at the University of Maryland, Department of Veterinary Medicine have developed a cell line that produces a monoclonal antibody (Mab) against Ehrlichia risticii which is the causative agent for Potomac Horse Fever. This Mab is well characterized and has high affinity for a specific Ehrlichia risticii protein. It can be used to develop...
Keyword(s): Ehrlichia risticii, Potomac horse fever, Veterinary Diagnostic (1AHV110), Monoclonal antibodies (1BIO110)
Docket: 02-87-031
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Modular Dexterous Hand
Published Tuesday, April 30, 1996Researchers at the University of Maryland, Institute of Systems Research, have designed and built a two-stage mechanism for grasping and fine manipulation of objects by robots.The "Modular Dexterous Hand" is useful in any application which requires grasping and precise manipulation of objects whose shape is not a design parameter...
Keyword(s): Robotic hand (2AUT160)
Docket: 02-88-030
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Pulsed Continuum Source-Diode Array Detector Multielement Atomic Absorption (AAS) Spectrometer
Published Tuesday, April 30, 1996Today, trace metals are being quantified at the ultra-trace level. Existing systems make accurate determinations at these levels laborious and predominantly single element processes, as typified by current commercially available atomic absorption spectroscopy (AAS) instruments. These instruments use a different hollow cathode lamp (HCL) for each...
Keyword(s): Spectrometer, Atomic absorption (2INS480), Trace element detector
Docket: 02-89-019
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Dual Mode Dielectric Resonator Filters without Iris
Published Tuesday, April 30, 1996Microwave narrow band-pass filters are used in a large variety of applications ranging from consumer electronics such as direct broadcast receivers and cellular telephones, to phased-array radar systems and satellite transponders. Currently, dual mode microwave filters require that physically adjacent dielectric resonators be coupled to each other...
Keyword(s): Microwave filters (3COM050)
Docket: 02-88-003
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Monoclonal Antibody Diagnostics for IBDV
Published Sunday, July 25, 1999It has been reported that researchers at the University of Maryland, College of Veterinary Medicine and the University of Maryland Biotechnology Institute’s Center for Agricultural Biotechnology, discovered a new type of Infectious Bursal Disease (IBD) virus. In identifying this new virus, a new bank of monoclonal antibodies was developed. These...
Keyword(s): 525
Docket: 02-88-033
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Continuous Particle Separation
Published Monday, April 12, 1999Separation of biological particles - specifically separation of Polyhedral Inclusion Bodies (PIBs) - from tissue and debris associated with production of virus using insect hosts, is a very difficult procedure. Typically separation is not accomplished. Instead the host insect is processed in its entirety leading to a very impure and diluted final...
Keyword(s): 525
Docket: 02-88-029
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Restriction Enzyme NgoMI
Published Tuesday, April 30, 1996A unique restriction enzyme, NgoM I, was isolated from Neisseria gonnorhoea. The DNA sequence of this gene has been identified, and the biological properties, stability, and yield of the enzyme have been determined. The enzyme recognition site is GCCGGC, and the cut cite is indicated by the open space G CCGGC.
Keyword(s): Restriction enzyme (1BIO220), DNA research reagent (1BIO190)
Docket: UM-91-006