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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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A Deformable Lung Motion Phantom
Published Friday, March 8, 2019Motion caused by patient breathing can limit the accuracy of the prescribed dose delivered during radiation therapy (RT) especially for cancers in the thorax and abdomen. Sophisticated respiratory motion prediction and real-time motion modeling have been clinically implemented to improve the accuracy and precision of the dose being delivered to...
Investigator(s): Amit Sawant, Maida Ranjbar, Pouya Sabouri, Carlo Repetto
Categories: Devices
Keyword(s): Radiation Oncology
Docket: AS-2018-044
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Adjustable Focus Magnetic Stimulation Coil
Published Friday, March 22, 2024Summary The Adjustable Focus Magnetic Stimulation Coil is a medical device for transcranial or transdermal magnetic stimulation (TMS) promising to enhance treatment of neurological disorders. Its unique coil design permits modulation of magnetic fields to penetrate deeper brain...
Investigator(s): L. Elliot Hong, Fow-Sen Choa, Qinglei Meng
Categories: Devices
Keyword(s): Transcranial Magnetic Stimulation (TMS), Neurological Diseases, Non-invasive Brain Stimulation
Docket: LH-2019-056
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Analyte Sensor Device and miniaturized Gel Holders, Methods and Systems Utilizing the Same
Published Tuesday, May 27, 2014Bioavailable metal ions (e.g. Cu2+, Zn2+) are essential nutrient required for the normal, healthy growth of plants, animals, and humans. Careful monitoring of these ions is often deployed to gauge levels within the environment to ensure safety as well as functionally adequate concentrations for economical utility. To quickly and easily monitor...
Investigator(s): Richard Thompson
Categories: Devices
Docket: RT-2007-027
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ANALYTE-SENSITIVE PROBES AND CONTACT LENS FOR DIAGNOSIS OF OCULAR PATHOLOGIES
Published Thursday, November 9, 2023Summary The patent introduces a contact lens integrated with analyte-sensitive probes for diagnosing ocular pathologies through the detection of specific analytes in basal tears. This non-invasive, real-time monitoring technology has applications in medical diagnostics and...
Investigator(s): Joseph R. Lakowicz, Ramachandram Badugu, E. Albert Reece
Categories: Devices, Imaging devices, Diagnostics, Imaging, Healthcare
Keyword(s): Analyte-sensitive probes, fluorescence, Diagnostics, Real-time monitoring
Docket: JL-2019-091
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Automatic CAD of Meniscal Tears on Magnetic Resonance Imaging: A Morphology- Based Approach
Published Tuesday, May 27, 2014Knee related injuries, including meniscal tears, are common in young athletes and elderly patients, and require accurate diagnosis for optimal treatment. With proper technique and skill, detection rates of meniscal tears are relatively high, but recognition relies on the experience of the physicians and continues to be a challenge for many...
Investigator(s): Nabile Safdar, Bharath Ramakrishna, Chein-I Chang, Wei-min Liu, Khan Siddiqui, Eliot Siegel
Categories: Devices, Imaging devices
Keyword(s): imaging
Docket: NS-2007-085
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Balanced Reach Control Systems Model
Published Tuesday, May 2, 2017Bipedal standing balance is inherently unstable and must be actively controlled to prevent falling. This involves a complex interaction of the sensorimotor system and multi-segment musculoskeletal system. Fall risk increases with deterioration of sensorimotor and musculoskeletal elements responsible for balance due to age, neurological...
Investigator(s): Joseph E. Barton
Categories: Devices, Imaging devices, Software + Algorithm, Methods of Treatment
Keyword(s): Rehabilitation, balance, reaching, Aging Population
Docket: JB-2016-005, JB-2016-004
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Bidirectional Flow Cannula
Published Thursday, January 31, 2019In order to accommodate the high blood flows in veno-arterial extracorporeal membrane circulation (VA ECMO) and cardiopulmonary bypass (CPB), large cannulae are inserted into a patient’s femoral vein, to drain blood to the system, and into the femoral artery to...
Investigator(s): Bartley Griffith, Zachary Kon, Chetan Pasrija, Mehrdad Ghoreishi, Gregory Bittle
Categories: Devices, Medical implants, Surgical devices, Methods of Treatment
Keyword(s): Cardiopulmonary, Life-support, ECMO
Docket: ZK-2017-057
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Biologically-Inspired Visually Implemented Blending in a Local Environment (B-InVisIBLE) Active Camouflage
Published Monday, October 29, 2007A flexible, conformable display mechanism has been described that is capable of creating a wide variety of color combinations and spatial patterns, which uses the chromatophores and reflective underlying layer of cuttlefish skin as biological inspiration. Basic operation is similar in concept to the operation of passive-matrix LCDs, whereby the...
Categories: Devices
Keyword(s): environment, artificial, cuttle fish, active camoflauge
Docket: PS-2007-070
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Case Mounting Stabilizers
Published Tuesday, May 27, 2014This device is used for relating casts, molds of the patient's mouth, which are used in the the construction of dentures, partial dentures, bridges, crowns, and implant restorations. No similar product is available, and dentists rely on improvised methods that are not always reliable.
Investigator(s): Sharon Siegel
Categories: Devices, Dental
Keyword(s): dental
Docket: SS-98-042
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Coherence-gated Doppler: A fiber sensor for precise localization of blood flow
Published Tuesday, May 27, 2014Coherence Gated Doppler (CGD) is an optical fiber sensor technology that combines the strengths of two optical technologies, the laser Doppler flowmetry (LDF) and the optical coherence tomography (OCT). The current LDF technology remains highly sensitive but suboptimal for localization of flow signals while the OCT and its Doppler variant, DOCT...
Investigator(s): Cha-Min Tang, Chia-Pin Liang, Yu Chen, Ashraf Fouad, Joseph Schmitt
Categories: Devices, Surgical devices
Docket: CT-2013-008