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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Real-Time Critical-Care Patient Vital Signs Viewer System
Published Monday, November 7, 2022Our team of trauma care specialists at University of Maryland, Baltimore built the “Real-Time Critical-Care Patient Vital Signs Viewer System” (the “VS Viewer”) as a custom-designed physiological data display system that allows for bedside and remote monitoring of critically ill patients. In fact, the system has reliably been running...
Investigator(s): Peter Hu, Shiming Yang, Colin Mackenzie, Thomas Scalea, Lynn Stansbury, Deborah Stein
Categories: Software + Algorithm, Healthcare, Sensors/Monitors
Keyword(s): Trauma care; remote monitor; clinical decision support tool
Docket: PH-2012-076
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Real-Time, 3-Dimensional, Massive Terrain and Dynamic Animated Data Visualization System
Published Monday, July 27, 2009Real-time transportation data visualization systems have been slow to evolve and current advanced traveler information systems (ATIS) and advanced traffic management systems (ATMS) still used 2D traffic maps to display a graphic of the local roads that are color coded to communicate speed and volume. Such a representation severely limits the end-...
Categories: Software + Algorithm, Information Technology
Keyword(s): traffic mapping, GIS, 525
Docket: IS-2008-020
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REVEAL - Research-Enhanced Virtual Environment for Acquiring Language
Published Wednesday, February 28, 2018Researchers at the University of Maryland have created REVEAL (Research-Enhanced Virtual Environment for Acquiring Language), a method and associated system for providing an immersive 360-degree cinematic video language training experience to individuals learning a foreign language or receiving training or therapy in their first language. The...
Categories: Software + Algorithm
Keyword(s): virtual reality, language learning
Docket: IS-2017-091
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Risk-Based Path Optimization
Published Wednesday, February 28, 2018Operating unmanned aerial vehicles (UAVs) over inhabited areas requires mitigating the risk to persons on the ground. Because the risk depends upon the flight path, UAV operators need approaches that can find low-risk flight paths between the mission’s start and finish points. Since the flight paths with the lowest risk could be excessively long...
Categories: Software + Algorithm
Keyword(s): unmanned aerial vehicles, risk, reduction, mitigation, path optimization
Docket: IS-2017-064
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Sailfish - A System for Estimating Gene Expression from RNA-Seq Reads
Published Thursday, May 3, 2018Sailfish implements an efficient, accelerated expectation-maximization algorithm for quantifying isoform abundance that produces high-quality results, and is capable of correcting numerous types of systematic bias that are known to occur in RNA-seq experiments. In the paper, we demonstrate that, on both real and synthetic data, Sailfish is as...
Categories: Software + Algorithm
Keyword(s): RNA, Gene Expression, estimation, open, source
Docket: IS-2017-155
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SILCS: Site Identification by Ligand Competitive Saturation. Method for binding site identification by molecular dynamics simulation
Published Thursday, May 29, 2014The present invention is directed to a method of computational chemistry for identifying binding sites by molecular dynamics simulations using ligand competitive saturation. Fragment-based drug discovery relies on a simple premise: identify small molecule fragments that bind to a target region of a large molecule and then evolve or link the...
Investigator(s): Alex MacKerell Jr., Olgun Guvench
Categories: Research Tools, Antibodies, & Reagents, Software + Algorithm
Keyword(s): simulation, drug design
Docket: AM-2009-054
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Simetric
Published Monday, December 19, 2016BackgroundChildren undergoing medical procedures experience stressful reactions that can impair treatment and recovery. Currently, hospitals employ various methods to reassure these children, including showing them the treatment room and talking them through the procedure. However, some hospitals lack the necessary resources to accomplish...
Categories: Software + Algorithm, Engineering
Keyword(s): virtual reality, procedure, stress, anxiety, treatment
Docket: IS-2016-073
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Simulated Electronic Health Record
Published Wednesday, February 28, 2018A large part of educating health professions students is preparing them for future practice. Much of today’s healthcare environment relies on technology, particularly an electronic health record (EHR). For the past several years, documentation during simulation events occurred through the use of paper charts, which is not consistent with current...
Categories: Software + Algorithm, Education/Training/Multimedia
Keyword(s): simulation, health
Docket: IS-2017-103
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SoundsRight CAPTCHA
Published Wednesday, July 31, 2019Executive SummaryAccording to the Centers for Disease Control and Prevention (CDC), 61 million adult Americans live with a disability. Of those people, 4.6 percent (approximately 2.8 million) people are visually disabled. These vision impairments, including blindness, lead to difficulty when using computers. One common difficulty is the...
Categories: Software + Algorithm
Keyword(s): CAPTCHA, accessibility
Docket: IS-2019-074
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Speaker Independent Speech Inversion System
Published Thursday, October 17, 2019BackgroundSpeech inversion is the process of mapping acoustic signals into articulatory parameters. This is a well-known ill-posed problem and the addition of individual speaker differences make it even harder to solve. Normalizing the speaker differences is essential to effectively using multi-speaker articulatory data for training a...
Categories: Software + Algorithm
Docket: IS-2019-031