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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Engineering Thermalization and Chemical Potential for Photons
Published Sunday, May 17, 2015Background:Due to the lack of photon number conservation, in thermodynamics of photons, the chemical potential is absent. However, having a non-zero chemical potential is crucial in understanding a wide variety of single and many-body effects, from transport in conductors and semi-conductors to phase transitions in electronic and atomic...
Categories: Engineering, Chemical
Keyword(s): optomechanics Quantum simulation
Docket: PS-2015-013
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Compressive Radar Imaging Technology
Published Sunday, June 29, 2014The military utilizes the mapping of targets and terrain to provide much needed information for its field operations. Synthetic Aperture Radar (SAR) has been used in this capacity to provide a quality map for these operations. Researchers in the Department of Electrical and Computer Engineering at the University of Maryland–College...
Categories: Software + Algorithm, Aerospace, Engineering
Keyword(s): defense, radar, compressed imaging, mapping, environmental monitoring
Docket: IS-2009-018
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Thermostabilization of DNA Polymerase with Novel Chaperones
Published Thursday, May 29, 2014Dr. Frank Robb has considerable expertise in the study of microbes found in extreme environments and their mechanisms of survival. These astonishing organisms have protein chaperone systems that enable them to survive and even thrive in extreme heat and harsh chemical conditions. An important application for these chaperones is to enhance...
Investigator(s): Frank Robb, Pongpan Laksanalamai
Categories: Research Tools, Antibodies, & Reagents, Engineering, Chemical
Docket: FR-2010-087
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Novel Filamentous Hyperstable Chaperone with Protein and Cellular Stabilization
Published Wednesday, May 28, 2014Ethanol, butanol, acetone and many other chemicals have traditionally been employed as a chemical feed stock for a variety of industrial chemicals. However, many of the byproducts produced during fermentation is cytotoxic and limits product generation. The disadvantages of low productivity, low cell density, longer fermentation, and prolonged...
Investigator(s): Frank Robb, Pongpan Laksanalamai, Anchalee Jiemjit, Douglas Clark, Timothy Whitehead
Categories: Engineering, Chemical
Docket: FR-2010-088
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Disruption of the microtubule network as a therapeutic intervention in the muscular dystrophies
Published Tuesday, May 27, 2014Across several muscular myopathies, such as Duchenne muscular dystrophy (DMD), Becker muscular dystrophy, and dysferlinopathies, intercellular signaling cascades such as reactive oxygen signaling (ROS) and calcium (Ca2+) are enhanced and contribute to the onset and pathogenic progression of the myopathy. The discovery of the...
Investigator(s): Christopher Ward, Ramzi Khairallah
Categories: Research Tools, Antibodies, & Reagents, Therapeutics, Biologics, Engineering, Bioengineering
Keyword(s): musculoskeletal, rare disease, muscular dystrophy
Docket: CW-2012-040
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Defect-free dendrimer synthesis through proportionate branching
Published Tuesday, May 27, 2014Dendrimers are nanoparticles of synthetic monomers with applications in commercial paints, blood substitutes, nanomaterials, sensor technology. Dendrimers are also building blocks for targeted drug or gene delivery. The dendrimers open architecture forms hollow cavities within the branches that can encapsulate molecules such as drugs or...
Investigator(s): Bruce Yu, Xuyi Yue
Categories: Imaging devices, Diagnostics, Platforms, Therapeutics, Engineering, Biomaterials
Docket: BY-2012-068
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Highly Energy-Dissipative Ductile (HED) Diagrid Framing System
Published Wednesday, October 3, 2012High rise buildings in high seismic zones are susceptible to destructive high energy forces during major and even smaller earthquakes. Constructing buildings using a system that has both inelastic qualities for strength and elastic qualities to provide a measure of flexibility during seismic activity would undoubtedly be beneficial....
Categories: Engineering, Industrial Processing
Keyword(s): diagrid framing, high seismic zones, earthquake loading
Docket: PS-2011-114
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Photovoltaic Energy Conversion Using Surface Acoustic Waves in Piezoelectric Semiconductors
Published Thursday, January 13, 2011The field of photovoltaic energy conversion is rapidly becoming more diverse. Improvements have been made in many existing devices in the form of traditional photovoltaic panels, and new fabrication techniques and materials have permitted researchers to explore different approaches in an attempt to combine improved efficiency of photovoltaic...
Categories: Microelectronics, Power Electronics, Materials, Engineering, Devices
Keyword(s): photovoltaics, surface acoustic wave, energy conversion
Docket: PS-2009-039
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Magnetostrictive Wire Based Flow Sensors
Published Tuesday, November 2, 2010Background:Numerous examples of cilia and whisker-based flow sensors can be found in nature. A mammal’s whisker bends in response to touch or to wind, creating a sensory response which is then interpreted by the animal’s brain. Similarly, fish have a sensory organ known as a lateral line running the length of the body that can detect...
Categories: Aerospace, Sensors/Monitors, Materials, Engineering
Keyword(s): magnetostrictive wires, sensors, medical devices, biological warning systems
Docket: PS-2010-055
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Nanolithography with Nanowire Arrays
Published Thursday, January 7, 2010BackgroundIntegrated circuits are used in nearly all electronic equipment currently in production. Also known as microchips, they control everything from computers to cell phones to microwave ovens. The performance of these chips depends on features that are only a few tens of nanometers across and that can be assembled in extremely close...
Categories: Nanotechnology + Nanoparticles + Nanomaterials, Industrial Processing, Engineering, Materials
Keyword(s): circuits, photon, nano, computer, chip
Docket: LS-2009-123