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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Biocompatible 3D Printing Resin at Physiologic Temperature
Published Sunday, June 19, 2016BackgroundCardiovascular disease (CVD) is the leading cause of death worldwide and congenital heart disease (CHD) is among the leading causes of death in newborns. In recent years, there have been complications with the use of synthetic materials such as artificial grafts or patches, two current treatments of CVD and CHD, which include...
Categories: Engineering, Biomaterials, Bioengineering, Biological
Keyword(s): Cardiovascular disease, 3D printing, vascular graft material, 3d printer resin, drug delivery system, cell growth scaffolds
Docket: PS-2016-028
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Immunotherapeutic Potential of Modified Lipooligosaccharides/Lipid A: A Platform for “Custom-designed Adjuvants”
Published Wednesday, November 12, 2014Lipid A, the hydrophobic anchor of lipopolysaccharide (LPS), can stimulate the innate immune system via Toll-like receptor 4/myeloid differentiation factor 2 (TLR4/MD2), leading to the release of inflammatory cytokines/chemokines and type I interferons. In turn, this response increases the host’s ability to eradicate a pathogen and supports...
Investigator(s): Robert K Ernst, Adeline Hajjar, Mark Pelletier
Categories: Platforms, Biologics, Vaccines, Biological, Vaccine, Other
Keyword(s): adjuvant, subunit vaccine, lipid A, platform, lipopolysaccharide, immunostimulation custom synthesis
Docket: RE-2012-067
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3D Printed Molds for 3D Tissue Culture Scaffolds
Published Tuesday, November 4, 2014BackgroundCellular and tissue culture is an important aspect of biological research. Having specific cell or tissue types in a controlled environment allows for development and refinement of the efficacy and safety of biological treatments. However, as researchers study more complex conditions, standard monolayer (2D) cell culture is...
Categories: Biological, Research Tools, Antibodies, & Reagents
Keyword(s): PDMS, stem cells, cell culture, tissue culture
Docket: LS-2014-073
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Teleoperated Robotic System for Image Guided Radiofrequency Ablation and Biopsy
Published Monday, May 18, 2009This invention will lead to the development of a multi-degree of freedom, tele-operated robotic system. This system will be compatible with any imaging modality such as, but not limited to, Magnetic Resonance Imaging, for performing radio frequency ablation, biopsy or any other intervention while under continuous image guidance. The robotic system...
Categories: Biological, Robotics, Surgical devices
Keyword(s): teleoperated robotic system image guided RF ablation biopsy
Docket: PS-2007-087