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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Magnetic nanoparticles in dentistry
Published Thursday, January 24, 2019University of Maryland clinical researchers saw a clear need to target therapeutic agents to dental tissues with a method that would avoid the need for an invasive procedure like a root canal. Drs. Masri and Depireux devised a platform strategy to actively deliver therapeutic payloads to the inner tooth, which relies on magnetic nanoparticles...
Investigator(s): Radi Masri, Didier Depireux
Categories: Devices, Medical implants, Drug delivery devices, Platforms, Materials, Dental
Docket: RM-2014-062
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Protein-Repellant Compositions to Inhibit Protein Absorption and Bacteria Attachment for Dental Applications
Published Thursday, February 23, 2017The mechanism underlying dental caries is demineralization through the attack by acid generated by acidogenic bacteria. Acidogenic bacteria growth typically occurs in plaque and biofilm. When biofilms forms at the tooth restoration margins, the demineralization of the enamel and dentin leads to secondary caries, restorative material fractures,...
Investigator(s): Huakun Xu, Ning Zhang
Categories: Medical implants, Dental
Keyword(s): Dental devices, Antibacterial materials
Docket: HX-2014-154
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Antibacterial monomers, antibacterial resins and dental composites comprising the antibacterial resins
Published Thursday, October 15, 2015A major clinical problem associated with dental restorations is secondary cary formation and tooth restoration fractures. To address this issue, a new dental resin developed at the University of Maryland, Baltimore, was created that possesses superior mechanical strength and antimicrobial properties. The formulation...
Investigator(s): Huakun Xu, Michael Weir
Categories: Dental
Keyword(s): dental, cary, restorative, composite
Docket: HX-2013-023
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Injectable Matrix for Load-Bearing Bone Repair
Published Wednesday, May 28, 2014Dr. Huakun Xu and his team at UMB have created an injectable and mechanically strong construct to be used with or without stem cells for bone tissue engineering. The UMB inventors have designed a strong, moldable, and injectable stem cell-containing scaffold for bone tissue engineering that can be used in...
Investigator(s): Huakun Xu, Michael Weir
Categories: Bioengineering, Dental
Keyword(s): bone repair, dental
Docket: HX-2010-041 & HX-2012-027
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Dental Nanocomposites and Bonding Agents with Antibacterial Properties
Published Tuesday, May 27, 2014The major clinical problem associated with dental restorations is secondary cary formation and tooth restoration fractures. To address this issue, a new dental resin developed at the University of Maryland, Baltimore, was created to possess superior mechanical strength and antimicrobial properties. The formulation...
Investigator(s): Huakun Xu, Michael Weir
Categories: Dental
Keyword(s): dental, antibacterial, remineralizing
Docket: HX-2010-042 & HX-2012-066
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Case Mounting Stabilizers
Published Tuesday, May 27, 2014This device is used for relating casts, molds of the patient's mouth, which are used in the the construction of dentures, partial dentures, bridges, crowns, and implant restorations. No similar product is available, and dentists rely on improvised methods that are not always reliable.
Investigator(s): Sharon Siegel
Categories: Devices, Dental
Keyword(s): dental
Docket: SS-98-042