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Researchers at the University of Maryland have created hundreds of innovations that are available for licensing. Our Discovery Portfolio contains an exciting mix of vaccines, drug targets, therapeutics, devices and cutting edge techniques that promise to make a quantifiable impact on human health and the environment.
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Combination Assessment of Volume Status (CAVS)
Published Wednesday, May 17, 2023Early and aggressive fluid resuscitation in shock is associated with improved patient outcome and mortality. However, there is a clear correlation between cumulative fluid balance and mortality. There is, therefore, a benefit to adopting a systematic approach to fluid resuscitation to determine which patients would benefit from a fluid bolus...
Investigator(s): Sarah Murthi
Categories: Diagnostics, Software + Algorithm
Keyword(s): CAVS, shock, ultrasound, POCUS
Docket: SM-2016-067
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BLEEDING RISK INDEX (BRI) PREDICTION ALGORITHM
Published Monday, November 7, 2022Hemorrhage is the most common cause of preventable death on the battlefield and in civilian trauma care. Triaging patients that may have life-threatening bleeding in the field is essential for distinguishing those who need trauma center care, early control of bleeding, and blood transfusion. The UMB inventors developed the Bleeding Risk Index (...
Investigator(s): Peter Hu, Colin Mackenzie, Shiming Yang, Hegang Chen, Konstantinos Kalpakis
Categories: Software + Algorithm, Healthcare
Keyword(s): Clinical decision support; blood transfusion; triage
Docket: PH-2014-007; PH-2016-074
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Real-Time Critical-Care Patient Vital Signs Viewer System
Published Monday, November 7, 2022Our team of trauma care specialists at University of Maryland, Baltimore built the “Real-Time Critical-Care Patient Vital Signs Viewer System” (the “VS Viewer”) as a custom-designed physiological data display system that allows for bedside and remote monitoring of critically ill patients. In fact, the system has reliably been running...
Investigator(s): Peter Hu, Shiming Yang, Colin Mackenzie, Thomas Scalea, Lynn Stansbury, Deborah Stein
Categories: Software + Algorithm, Healthcare, Sensors/Monitors
Keyword(s): Trauma care; remote monitor; clinical decision support tool
Docket: PH-2012-076
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Speaker Independent Speech Inversion System
Published Thursday, October 17, 2019BackgroundSpeech inversion is the process of mapping acoustic signals into articulatory parameters. This is a well-known ill-posed problem and the addition of individual speaker differences make it even harder to solve. Normalizing the speaker differences is essential to effectively using multi-speaker articulatory data for training a...
Categories: Software + Algorithm
Docket: IS-2019-031
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SoundsRight CAPTCHA
Published Wednesday, July 31, 2019Executive SummaryAccording to the Centers for Disease Control and Prevention (CDC), 61 million adult Americans live with a disability. Of those people, 4.6 percent (approximately 2.8 million) people are visually disabled. These vision impairments, including blindness, lead to difficulty when using computers. One common difficulty is the...
Categories: Software + Algorithm
Keyword(s): CAPTCHA, accessibility
Docket: IS-2019-074
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Noninvasive Characterization of Mechanical Properties of Materials and Tissue using Magnetic Resonance Techniques
Published Wednesday, February 6, 2019Many diseases alter the mechanical properties of tissue. Accordingly, the mechanical properties can serve as biomarkers for disease, diagnosis, and tumor assessment. While some larger diseased tissues or abnormalities near the surface of a patient can be detected by palpitation, many are located deep within the patient or too small to...
Investigator(s): Bruce Yu, Mark Taraban, Yue Feng
Categories: Devices, Software + Algorithm, Sensors/Monitors, Industrial Processing, Other
Keyword(s): MRI, NMR, diagnostic
Docket: BY-2012-013
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Programmatic Interface to Digitimer DS8R and Compatible Devices
Published Wednesday, January 9, 2019This software library is a programmatic interface that allows for the control of various settings of the DS8R Biphasic Constant Current Stimulator produced by Digitimer Ltd. and other compatible devices. This interface consists of two parts. The first part is a wrapper API that interacts with DLL supplied by Digitimer. The second part uses...
Categories: Software + Algorithm
Docket: IS-2018-155
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libASPP: The Asynchronous Standard Parallel Port Library
Published Tuesday, January 8, 2019The Asynchronous Standard Parallel Port Library (libASPP) is a module developed at the University of Maryland that asynchronously sends various event signals to other devices for data synchronization. The asynchronous signal transfer feature is implemented using a multiple timer queue, which allows the sender to process its algorithms and data...
Categories: Software + Algorithm
Docket: IS-2018-118
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An Easy-to-Deploy Temporal Thermographic Data Collection and Analysis System
Published Thursday, May 3, 2018Buildings in the United States consume a significant amount of energy and release an increasing amount of CO2. Accordingly, tools and techniques have been developed to determine where energy efficiency in buildings can be improved. One such technique is thermography, where auditors determine energy inefficiency using a thermal camera that shows...
Categories: Software + Algorithm, Information Technology
Keyword(s): temporal, thermography, visualization, energy, efficiency
Docket: PS-2017-069
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Sailfish - A System for Estimating Gene Expression from RNA-Seq Reads
Published Thursday, May 3, 2018Sailfish implements an efficient, accelerated expectation-maximization algorithm for quantifying isoform abundance that produces high-quality results, and is capable of correcting numerous types of systematic bias that are known to occur in RNA-seq experiments. In the paper, we demonstrate that, on both real and synthetic data, Sailfish is as...
Categories: Software + Algorithm
Keyword(s): RNA, Gene Expression, estimation, open, source
Docket: IS-2017-155